Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 4/20 | 0.53 |
| ▸ | AGTR2 | P50052 | 4/20 | 0.53 |
| ▸ | PPARG | P37231 | 8/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9119861 | 0.87 | AGTR1 (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL5864446 | 0.85 | AGTR1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL6777744 | 0.83 | TBXA2R (0.52) | — | |
| SCHEMBL8411049 | 0.83 | USP2 (0.55) | — | |
| SCHEMBL6215697 | 0.81 | ALDH1A1 (0.48) | AGTR1AGTR2PPARGALDH1A1TDP1 | |
| SCHEMBL5864345 | 0.80 | POLB (0.44) | AGTR1AGTR2PPARGALDH1A1TDP1 | |
| SCHEMBL5864337 | 0.80 | POLB (0.43) | AGTR1AGTR2PPARGALDH1A1TDP1 | |
| SCHEMBL9740603 | 0.79 | ALDH1A1 (0.66) | AGTR1AGTR2ALDH1A1TDP1 | |
| SCHEMBL5864747 | 0.79 | ALDH1A1 (0.40) | AGTR1AGTR2PPARGALDH1A1TDP1 | |
| SCHEMBL5864750 | 0.79 | ALDH1A1 (0.40) | AGTR1AGTR2PPARGALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984642-B1 | Substituted phenylcyclohexane carboxylic acid amides and their use as adenosine uptake inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 2006-01-10 | — | — | US | disclosed |