Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR1 | P30556 | 6/20 | 0.48 |
| ▸ | AGTR2 | P50052 | 6/20 | 0.48 |
| ▸ | PPARG | P37231 | 6/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5864485 | 0.85 | AGTR1 (0.53) | AGTR1AGTR2PPARG | |
| SCHEMBL9119861 | 0.82 | AGTR1 (0.64) | AGTR1AGTR2PPARG | |
| SCHEMBL6777744 | 0.77 | TBXA2R (0.52) | TBXA2RALOX5AP | |
| SCHEMBL8411049 | 0.76 | USP2 (0.55) | TBXA2RALOX5AP | |
| SCHEMBL9121396 | 0.74 | AGTR1 (0.58) | AGTR1AGTR2PPARGTBXA2R | |
| SCHEMBL6215697 | 0.74 | ALDH1A1 (0.48) | AGTR1AGTR2PPARG | |
| SCHEMBL9088763 | 0.73 | AGTR1 (0.57) | AGTR1AGTR2PPARG | |
| SCHEMBL5864383 | 0.73 | PDE6D (0.51) | — | |
| SCHEMBL6797313 | 0.72 | PTAFR (0.43) | TBXA2RALOX5AP | |
| SCHEMBL8977019 | 0.70 | AGTR2 (0.50) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6984642-B1 | Substituted phenylcyclohexane carboxylic acid amides and their use as adenosine uptake inhibitors | BAYER AKTIENGESELLSCHAFT (DE) | 2006-01-10 | — | — | US | disclosed |