Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | BLM | P54132 | 3/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | ERN1 | O75460 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
| ▸ | THPO | P40225 | 1/20 | 0.36 |
| ▸ | NCF1 | P14598 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2255938 | 0.90 | KDM4E (0.48) | MAPTKDM4ECYP3A4LMNABLM | |
| SCHEMBL13154641 | 0.76 | NOTUM (0.40) | KDM4ECYP3A4NOTUMBCHEACHE | |
| SCHEMBL13154665 | 0.75 | NOTUM (0.42) | NOTUMBCHEACHEPKM | |
| SCHEMBL13154666 | 0.74 | NOTUM (0.44) | MAPTKDM4ECYP3A4LMNABLM | |
| SCHEMBL582334 | 0.72 | NOTUM (0.46) | KDM4ELMNAHIF1AMEN1KMT2A | |
| SCHEMBL13154679 | 0.71 | LMNA (0.52) | MAPTKDM4ECYP3A4LMNAHIF1A | |
| SCHEMBL7375651 | 0.71 | MAPT (0.52) | MAPTKDM4ECYP3A4LMNABLM | |
| SCHEMBL1010220 | 0.71 | MAPT (0.43) | MAPTKDM4ECYP3A4LMNABLM | |
| SCHEMBL5773101 | 0.71 | GSK3B (0.51) | MAPTKDM4ELMNABLMHIF1A | |
| SCHEMBL217044 | 0.71 | MAPT (1.00) | MAPTKDM4ECYP3A4LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | UDC IRELAND LIMITED (IE) | 2024-05-07 | — | — | US | disclosed |
| US-20240074302-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | UDC IRELAND LTD (IE) | 2024-02-29 | — | — | US | disclosed |
| WO-2022238696-A1 | RADIATION-ACTIVATABLE COMPOUNDS AND USES THEREOF | THE UNIVERSITY COURT OF THE UNIVERSITY OF EDINBURGH (GB) | 2022-11-17 | — | — | WO | disclosed |
| US-20140309428-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | BASF SE (DE) | 2014-10-16 | — | — | US | disclosed |
| US-7803948-B2 | Method for the isomerisation of transition metal complexes containing cyclometallated, carbene ligands | BASF AKTIENGESELLSCHAFT (DE) | 2010-09-28 | — | — | US | disclosed |
| US-20080200686-A1 | Method for the Isomerisation of Transition Metal Complexes Containing Cyclometallated, Carbene Ligands | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| US-20080018221-A1 | Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) | BASF AKTIENGESELLSCHAFT (DE) | 2008-01-24 | — | — | US | disclosed |
| US-7064117-B2 | Anti-cancer 2,3-dihydro-1H-pyrrolo[3,2-f]quinoline complexes of cobalt and chromium | AUCKLAND UNISERVICES LIMITED (NZ) | 2006-06-20 | — | — | US | disclosed |
| US-20050038249-A1 | Anti-cancer 2,3-dihydro-1H-pyrrole[3,2-f] quinoline compolexes of cobalt and chromium | AUCKLAND UNISERVICES LIMITED (NZ) | 2005-02-17 | — | — | US | disclosed |
| US-20040138195-A1 | Anti-cancer 2,3-dihydro-1h-pyrrolo[3,2-f[quinoline complexes of cobalt and chromium | AUCKLAND UNISERVICES LIMITED (NZ) | 2004-07-15 | — | — | US | disclosed |
| EP-1363908-A4 | ANTI-CANCER 2,3-DIHYDRO-1H-PYRROLO 3,2-f]QUINOLINE COMPLEXES OF COBALT AND CHROMIUM | AUCKLAND UNISERVICES LTD (NZ) | 2004-05-06 | — | — | EP | disclosed |
| EP-1363908-A1 | ANTI-CANCER 2,3-DIHYDRO-1H-PYRROLO 3,2-f]QUINOLINE COMPLEXES OF COBALT AND CHROMIUM | Auckland Uniservices Limited (NZ) | 2003-11-26 | — | — | EP | disclosed |
| WO-2002059122-A1 | ANTI-CANCER 2,3-DIHYDRO-1H-PYRROLO[3,2-f]QUINOLINE COMPLEXES OF COBALT AND CHROMIUM | AUCKLAND UNISERVICES LIMITED (NZ) | 2002-08-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138195-A1 | Anti-cancer 2,3-dihydro-1h-pyrrolo[3,2-f[quinoline complexes of cobalt and chromium | IDH1, HIF1AN, CA2 | MAPT 4825/4885KDM4E 784/4885CYP3A4 282/4885 |
| US-20080200686-A1 | Method for the Isomerisation of Transition Metal Complexes Containing Cyclometallated, Carbene Ligands | SCO2, CYC1, CHRM1 | MAPT 4777/4885KDM4E 4387/4885CYP3A4 731/4885 |
| US-11980086-B2 | Use of transition metal carbene complexes in organic light-emitting diodes (OLEDs) | OCIAD2, OCIAD1, ICOSLG | MAPT 414/4885KDM4E 4325/4885CYP3A4 711/4885 |
| US-20080018221-A1 | Use Of Transition Metal Carbene Complexes In Organic Light-Emitting Diodes (Oleds) | OCIAD2, OCIAD1, ICOSLG | MAPT 414/4885KDM4E 4325/4885CYP3A4 711/4885 |
| US-20240074302-A1 | USE OF TRANSITION METAL CARBENE COMPLEXES IN ORGANIC LIGHT-EMITTING DIODES (OLEDS) | OCIAD2, OCIAD1, ICOSLG | MAPT 414/4885KDM4E 4325/4885CYP3A4 711/4885 |
| US-20050038249-A1 | Anti-cancer 2,3-dihydro-1H-pyrrole[3,2-f] quinoline compolexes of cobalt and chromium | CA2, HIF1AN, PPOX | MAPT 4817/4885KDM4E 331/4885CYP3A4 355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.