Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KMO | O15229 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 1/20 | 0.35 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.35 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.34 |
| ▸ | RAPGEF3 | O95398 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865640 | 0.88 | NPFFR2 (0.44) | CYP3A4TSHRMAPK1ATML3MBTL1 | |
| SCHEMBL5865618 | 0.87 | CYP3A4 (0.57) | CYP3A4TSHRMAPK1ATML3MBTL1 | |
| SCHEMBL5865631 | 0.86 | NOTUM (0.53) | CYP3A4TSHRMAPK1ATML3MBTL1 | |
| SCHEMBL5865578 | 0.84 | MAPT (0.46) | CYP3A4TSHRMAPK1ATML3MBTL1 | |
| SCHEMBL5865588 | 0.78 | CYP3A4 (0.53) | CYP3A4TSHRMAPK1ATML3MBTL1 | |
| SCHEMBL10532934 | 0.76 | KMO (0.43) | TSHRNOTUMKMOKIF11MRGPRX4 | |
| SCHEMBL5865199 | 0.76 | CYP3A4 (0.55) | CYP3A4TSHRMAPK1ATML3MBTL1 | |
| SCHEMBL29589267 | 0.75 | NT5E (0.46) | CYP3A4TSHRMAPK1NOTUMKMO | |
| SCHEMBL585377 | 0.75 | NT5E (0.46) | CYP3A4TSHRMAPK1NOTUMKMO | |
| SCHEMBL9494805 | 0.75 | TSHR (0.59) | CYP3A4TSHRMAPK1ATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091248-B2 | Treatment of adrenocortical hypersecretion and tumor growth | BRANDT INGVAR | 2006-08-15 | — | — | US | disclosed |
| US-20040242705-A1 | Novel treatment of adrenocortical hypersecretion and tumour growth | BRANDT INGVAR (SE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242705-A1 | Novel treatment of adrenocortical hypersecretion and tumour growth | NR3C2, NR5A1, NR3C1 | CYP3A4 519/4885TSHR 118/4885MAPK1 2454/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.