Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VCAM1 | P19320 | 2/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAF1 | P04049 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.50 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | BCR | P11274 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5865653 | 0.88 | ALDH1A1 (0.48) | VCAM1GPR35ALDH1A1MAPTHPGD | |
| SCHEMBL5865624 | 0.88 | VCAM1 (0.66) | VCAM1GPR35ALDH1A1MAPTHPGD | |
| SCHEMBL5865402 | 0.87 | GPR35 (0.53) | VCAM1GPR35ALDH1A1MAPTLMNA | |
| SCHEMBL25962639 | 0.85 | VCAM1 (0.81) | VCAM1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL5865690 | 0.84 | GPR35 (0.49) | VCAM1GPR35ALDH1A1MAPTLMNA | |
| SCHEMBL1981879 | 0.81 | VCAM1 (0.60) | VCAM1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL5865568 | 0.79 | GPR35 (0.51) | VCAM1GPR35ALDH1A1MAPTMAPK1 | |
| SCHEMBL922714 | 0.79 | VCAM1 (0.77) | VCAM1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL1455196 | 0.79 | KMT2A (0.73) | VCAM1ALDH1A1MAPTHPGDLMNA | |
| SCHEMBL1258621 | 0.77 | VCAM1 (1.00) | VCAM1ALDH1A1MAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7091248-B2 | Treatment of adrenocortical hypersecretion and tumor growth | BRANDT INGVAR | 2006-08-15 | — | — | US | disclosed |
| US-20040242705-A1 | Novel treatment of adrenocortical hypersecretion and tumour growth | BRANDT INGVAR (SE) | 2004-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040242705-A1 | Novel treatment of adrenocortical hypersecretion and tumour growth | NR3C2, NR5A1, NR3C1 | VCAM1 1388/4885GPR35 263/4885ALDH1A1 570/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.