SCHEMBL5865768

SCHEMBL5865768

N#CC(C#N)=Cc1cccc(C=C(C#N)C#N)c1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 10/20 0.65
MAPT P10636 10/20 0.65
KMT2A Q03164 9/20 0.65
MEN1 O00255 8/20 0.65
KDM4E B2RXH2 6/20 0.65
LMNA P02545 5/20 0.65
NPSR1 Q6W5P4 4/20 0.65
POLB P06746 2/20 0.65
EGFR P00533 7/20 0.61
CYP3A4 P08684 5/20 0.61
HPGD P15428 5/20 0.61
BLM P54132 5/20 0.61
TSHR P16473 4/20 0.61
NFKB1 P19838 4/20 0.61
PMP22 Q01453 4/20 0.61
CYP2C9 P11712 4/20 0.61
HSD17B10 Q99714 4/20 0.61
SMN1; SMN2 Q16637 4/20 0.61
CYP1A2 P05177 4/20 0.61
TP53 P04637 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17466928 0.90 ALDH1A1 (0.54) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL8543873 0.87 EGFR (0.64) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL30729660 0.86 MAPT (0.54) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL6492531 0.86 FBP1 (0.55) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL3368325 0.86 KMT2A (0.56) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL3368556 0.86 KMT2A (0.54) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL30457529 0.86 KMT2A (0.56) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL29851854 0.86 KMT2A (0.54) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL3368267 0.86 MAPT (0.54) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL6489245 0.86 MAPT (0.54) ALDH1A1MAPTKMT2AMEN1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230059696-A1 ELECTROPHOTOGRAPHIC PHOTOSENSITIVE MEMBER, PROCESS CARTRIDGE, AND ELECTROPHOTOGRAPHIC APPARATUS CANON KABUSHIKI KAISHA (JP) 2023-02-23 US disclosed
EP-3172272-B1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & CO (US) 2020-11-25 EP disclosed
US-9410035-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2016-08-09 US disclosed
US-9410035-B2 Modified heterophasic polyolefin composition MILLIKEN & COMPANY (US) 2016-08-09 US disclosed
US-20160024289-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY 2016-01-28 US disclosed
WO-2016014122-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY (US) 2016-01-28 WO disclosed
US-20160024289-A1 MODIFIED HETEROPHASIC POLYOLEFIN COMPOSITION MILLIKEN & COMPANY 2016-01-28 US disclosed
US-7041419-B2 Charge transfer compounds, charge generating compound and polymer MINOLTA CO., LTD. (JP) 2006-05-09 US disclosed
US-20030087171-A1 Organic photoreceptor unit MINOLTA CO., LTD. (JP) 2003-05-08 US disclosed