Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | SCN4A | P35499 | 4/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TLR4 | O00206 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21775788 | 0.90 | ALDH1A1 (0.33) | PTGS1PTGS2ALDH1A1GAAHPGD | |
| SCHEMBL23627378 | 0.87 | GAA (0.32) | PTGS1PTGS2ALDH1A1GAAHPGD | |
| SCHEMBL25926103 | 0.82 | PTGS1 (0.33) | PTGS1PTGS2ALDH1A1GAAHPGD | |
| SCHEMBL8161008 | 0.82 | POLB (0.39) | PTGS1PTGS2ALDH1A1GAAHPGD | |
| SCHEMBL472102 | 0.82 | PTGS1 (0.38) | PTGS1PTGS2ALDH1A1GAAHPGD | |
| SCHEMBL21775778 | 0.81 | PTGS1 (0.31) | PTGS1PTGS2 | |
| SCHEMBL21888875 | 0.80 | MGLL (0.42) | ALDH1A1GAAHPGDLMNANPSR1 | |
| SCHEMBL14394607 | 0.78 | ALDH1A1 (0.36) | PTGS1PTGS2ALDH1A1GAAHPGD | |
| SCHEMBL12299699 | 0.78 | PTGS1 (0.36) | PTGS1PTGS2ALDH1A1GAAHPGD | |
| SCHEMBL262332 | 0.78 | MEN1 (0.41) | PTGS1PTGS2ALDH1A1GAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7049388-B2 | Process for manufacturing an α-dihydroxy derivative and epoxy resins prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-05-23 | — | — | US | claimed |
| US-6646102-B2 | Epoxidizing an alpha - halohydrin intermediate produced from a halide substitution of an alpha -dihydroxy derivative which has been obtained by a dihydroxylation reaction of an aryl allyl ether, oxidation catalysts | DOW GLOBAL TECHNOLOGIES INC. | 2003-11-11 | — | — | US | claimed |
| US-20030105268-A1 | Process for manufacturing an alpha-dihydroxy derivative and epoxy resins prepared therefrom | DOW GLOBAL TECHNOLOGIES INC. | 2003-06-05 | — | — | US | claimed |