Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRA | P16234 | 2/20 | 0.46 |
| ▸ | KDR | P35968 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | FGFR1 | P11362 | 3/20 | 0.45 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5749766 | 0.89 | MEN1 (0.51) | KDRSMN1; SMN2HTR2AHTR2CLMNA | |
| SCHEMBL5747258 | 0.86 | FGFR1 (0.48) | PDGFRASMN1; SMN2FGFR1PDGFRBSRC | |
| SCHEMBL5749184 | 0.85 | ALDH1A1 (0.51) | PDGFRAFGFR1PDGFRBSRCHTR2A | |
| SCHEMBL5751015 | 0.84 | FGFR1 (0.63) | PDGFRAKDRFGFR1PDGFRBSRC | |
| SCHEMBL5748530 | 0.84 | ABL1 (0.53) | PDGFRAKDRFGFR1PDGFRBSRC | |
| SCHEMBL5751620 | 0.82 | ADORA3 (0.47) | KDRFGFR1PDGFRBLMNAKMT2A | |
| SCHEMBL5751374 | 0.81 | IMPDH2 (0.48) | SMN1; SMN2LMNACYP1A2CYP2C19TDP1 | |
| SCHEMBL5746964 | 0.81 | IMPDH2 (0.47) | PDGFRASMN1; SMN2FGFR1PDGFRBCYP1A2 | |
| SCHEMBL5748516 | 0.80 | IMPDH2 (0.50) | SMN1; SMN2FGFR1LMNAKMT2AMEN1 | |
| SCHEMBL5749355 | 0.80 | LMNA (0.49) | PDGFRASMN1; SMN2FGFR1PDGFRBSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7005434-B2 | Compounds and uses thereof | SB CORPORATION (US) | 2006-02-28 | — | — | US | disclosed |
| US-20040048888-A1 | Novel compounds and uses thereof | SMITHKLINE BEECHAM CORPORATION | 2004-03-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040048888-A1 | Novel compounds and uses thereof | TEK, TIE1, KDR | PDGFRA 8/4885KDR 3/4885SMN1; SMN2 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.