Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | MME | P08473 | 3/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | TACR3 | P29371 | 8/20 | 0.43 |
| ▸ | ASPH | Q12797 | 1/20 | 0.43 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.43 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TACR2 | P21452 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5867334 | 1.00 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL5867677 | 0.87 | MME (0.54) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL5867674 | 0.87 | MME (0.54) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL27505417 | 0.83 | APAF1 (0.53) | MME | |
| Biphenyl SCHEMBL2328203 | 0.78 | MME (0.42) | MME | |
| SCHEMBL21722104 | 0.76 | C3AR1 (0.46) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL30178241 | 0.75 | LMNA (0.55) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL26638286 | 0.75 | LMNA (0.59) | KDM4EALDH1A1LMNAHPGDTSHR | |
| SCHEMBL10620657 | 0.75 | MME (0.50) | ALDH1A1MMETACR3 | |
| SCHEMBL29224714 | 0.75 | MME (0.58) | KDM4EALDH1A1LMNAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1379214-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING SAME | L'OREAL, S.A. (FR) | 2004-01-14 | — | — | EP | claimed |
| US-20020159962-A1 | Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same | L'OREAL S.A. (FR) | 2002-10-31 | — | — | US | claimed |
| WO-2002067875-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING THE SAME | L'OREAL S.A. (FR) | 2002-09-06 | — | — | WO | claimed |
| US-7118736-B2 | Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same | L'OREAL (FR) | 2006-10-10 | — | — | US | disclosed |
| EP-1379214-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING SAME | L'OREAL, S.A. (FR) | 2004-01-14 | — | — | EP | disclosed |
| US-20020159962-A1 | Hair relaxer compositions comprising at least one hydroxide compound and at least one activating agent, and methods of using the same | L'OREAL S.A. (FR) | 2002-10-31 | — | — | US | disclosed |
| WO-2002067875-A1 | HAIR RELAXER COMPOSITIONS COMPRISING AT LEAST ONE HYDROXIDE COMPOUND AND AT LEAST ONE ACTIVATING AGENT, AND METHODS OF USING THE SAME | L'OREAL S.A. (FR) | 2002-09-06 | — | — | WO | disclosed |
| US-4992267-A | Mixture of alkali metal hydroxide and disulfide reducing agent | JOHNSON PRODUCTS CO., INC. (US) | 1991-02-12 | — | — | US | disclosed |