SCHEMBL5868436

SCHEMBL5868436

CCCCCCCCC=CCCCCCCCC(=O)OCCN(C)CCOC(=O)CCCCCCCC=CCCCCCCCC

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNM1 Q05193 1/20 0.69
DGKA P23743 2/20 0.61
MGLL Q99685 1/20 0.60
MAPT P10636 3/20 0.58
ALDH1A1 P00352 1/20 0.58
THRB P10828 1/20 0.58
CNR1 P21554 1/20 0.58
PRKCE Q02156 1/20 0.55
PRKCQ Q04759 1/20 0.55
PRKCD Q05655 1/20 0.55
PRKCA P17252 1/20 0.55
EPHX2 P34913 1/20 0.54
TERT O14746 3/20 0.53
BLM P54132 2/20 0.53
HSD17B10 Q99714 2/20 0.53
FABP4 P15090 2/20 0.53
PTPN1 P18031 2/20 0.53
PPARG P37231 2/20 0.53
PPARD Q03181 2/20 0.53
PPARA Q07869 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5868433 1.00 DNM1 (0.69) DNM1DGKAMGLLMAPTALDH1A1
Hydrochloric Acid SCHEMBL5868346 0.98 DNM1 (0.67) DNM1DGKAMGLLMAPTALDH1A1
Hydrochloric Acid SCHEMBL5868342 0.98 DNM1 (0.67) DNM1DGKAMGLLMAPTALDH1A1
SCHEMBL20017916 0.97 DNM1 (0.65) DNM1DGKAMGLLMAPTALDH1A1
SCHEMBL17298644 0.96 DNM1 (0.63) DNM1DGKAMGLLMAPTALDH1A1
SCHEMBL14759950 0.96 MGLL (0.68) DNM1DGKAMGLLMAPTALDH1A1
SCHEMBL14759951 0.96 MGLL (0.68) DNM1DGKAMGLLMAPTALDH1A1
SCHEMBL5345533 0.94 MGLL (0.62) DNM1DGKAMGLLMAPTALDH1A1
SCHEMBL17401278 0.94 DNM1 (0.70) DNM1DGKAMGLLMAPTALDH1A1
SCHEMBL5345531 0.94 MGLL (0.62) DNM1DGKAMGLLMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2567951-B1 CATIONIC LIPID KYOWA HAKKO KIRIN CO LTD (JP) 2018-09-19 EP disclosed
EP-3301086-A1 PRODUCTION OF A COMPOSITION CONTAINING A COMPLEX BETWEEN A MEMBRANE COMPOSED OF A LIPID MONOLAYER AND A NUCLEIC ACID, AND, A LIPID MEMBRANE FOR ENCAPSULATING THE COMPLEX THEREIN Kyowa Hakko Kirin Co., Ltd. (JP) 2018-04-04 EP disclosed
US-9920028-B2 Cationic lipid KYOWA HAKKO KIRIN CO., LTD. (JP) 2018-03-20 US disclosed
US-9845306-B2 Cationic lipid KYOWA HAKKO KIRIN CO., LTD. (JP) 2017-12-19 US disclosed
US-20170349532-A1 CATIONIC LIPID KYOWA HAKKO KIRIN CO., LTD. (JP) 2017-12-07 US disclosed
US-20160304487-A1 CATIONIC LIPID KYOWA HAKKO KIRIN CO LTD (JP) 2016-10-20 US disclosed
US-9408914-B2 Cationic lipid KYOWA HAKKO KIRIN CO., LTD. (JP) 2016-08-09 US disclosed
US-20150343062-A1 CATIONIC LIPID KYOWA HAKKO KIRIN CO LTD (JP) 2015-12-03 US disclosed
EP-2774912-A1 CATIONIC LIPID Kyowa Hakko Kirin Co., Ltd. (JP) 2014-09-10 EP disclosed
US-20130280305-A1 CATIONIC LIPID KYOWA HAKKO KIRIN CO., LTD. (JP) 2013-10-24 US disclosed
US-20130108685-A1 CATIONIC LIPID KYOWA KIRIN CO., LTD. (JP) 2013-05-02 US disclosed
EP-2567951-A1 CATIONIC LIPID Kyowa Hakko Kirin Co., Ltd. (JP) 2013-03-13 EP disclosed
US-6998381-B2 Concentrated, stable, preferably clear, fabric softening composition containing amine fabric softener THE PROCTER & GAMBLE COMPANY (US) 2006-02-14 US disclosed
US-20040002436-A1 Concentrated, stable, preferably clear, fabric softening composition containing amine fabric softener THE PROCTER & GAMBLE COMPANY 2004-01-01 US disclosed
US-6630441-B2 Neutralized water insoluble amine fabric softener active containing at least two C6-C22 hydrocarbyl groups, no more than one being less than C12 and then the other at least C16; material that increases cationic charge density THE PROCTER & GAMBLE COMPANY 2003-10-07 US disclosed
US-20020155983-A1 CONCENTRATED, STABLE, PREFERABLY CLEAR, FABRIC SOFTENING COMPOSITION CONTAINING AMINE FABRIC SOFTENER PROCTER & GAMBLE COMPANY, THE 2002-10-24 US disclosed
EP-1002035-A1 CONCENTRATED, STABLE, PREFERABLY CLEAR, FABRIC SOFTENING COMPOSITION CONTAINING AMINE FABRIC SOFTENER THE PROCTER & GAMBLE COMPANY (US) 2000-05-24 EP disclosed
WO-1999006509-A1 CONCENTRATED, STABLE, PREFERABLY CLEAR, FABRIC SOFTENING COMPOSITION CONTAINING AMINE FABRIC SOFTENER THE PROCTER & GAMBLE COMPANY (US) 1999-02-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304487-A1 CATIONIC LIPID LPAR3, ACOX3, H1-3 DNM1 1201/4885DGKA 2516/4885MGLL 80/4885
US-20170349532-A1 CATIONIC LIPID LPAR3, ACOX3, H1-3 DNM1 1201/4885DGKA 2516/4885MGLL 80/4885
US-20130108685-A1 CATIONIC LIPID LPAR3, ACOX3, H1-3 DNM1 1201/4885DGKA 2516/4885MGLL 80/4885
US-20130280305-A1 CATIONIC LIPID LPAR3, ACOX3, H1-3 DNM1 1201/4885DGKA 2516/4885MGLL 80/4885
US-20150343062-A1 CATIONIC LIPID ACOX3, LPAR3, ELOVL3 DNM1 941/4885DGKA 2367/4885MGLL 96/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.