Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5870140 | 0.79 | KMT2A (0.54) | KMT2AKDM4EMAPTHPGDTP53 | |
| SCHEMBL5870615 | 0.76 | PLK1 (0.37) | — | |
| SCHEMBL11537614 | 0.68 | ALDH1A1 (0.50) | KMT2AKDM4EMAPTHPGDPOLB | |
| SCHEMBL951202 | 0.67 | FLT3 (0.67) | KMT2AKDM4ESMN1; SMN2MEN1ALDH1A1 | |
| SCHEMBL28053365 | 0.66 | HPGD (0.68) | KMT2AKDM4EMAPTHPGDTP53 | |
| SCHEMBL13932522 | 0.66 | ALDH1A1 (0.78) | KMT2AKDM4EMAPTHPGDPOLB | |
| SCHEMBL11379479 | 0.65 | KDM4E (0.48) | KMT2AKDM4EMAPTHPGDTP53 | |
| SCHEMBL11015201 | 0.65 | KMT2A (0.53) | KMT2AKDM4EMAPTHPGDPOLB | |
| SCHEMBL12630170 | 0.64 | KDM4E (0.57) | KMT2AKDM4EHPGDTP53POLB | |
| SCHEMBL7044700 | 0.63 | SMN1; SMN2 (0.52) | KMT2AKDM4EHPGDTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7078528-B2 | Biimidazole diamide anion binding agents | EAST CAROLINA UNIVERSITY (US) | 2006-07-18 | — | — | US | disclosed |
| US-20050004370-A1 | Biimidazole diamide anion binding agents | EAST CAROLINA UNIVERSITY | 2005-01-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050004370-A1 | Biimidazole diamide anion binding agents | ABCG2, BRI3BP, SLCO1B3 | KMT2A 4248/4885KDM4E 4206/4885MAPT 2493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.