Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | KLK1 | P06870 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | SCD | O00767 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7042640 | 0.84 | SMN1; SMN2 (0.46) | SMN1; SMN2ALDH1A1L3MBTL1HPGDKMT2A | |
| SCHEMBL7044623 | 0.83 | NPC1 (0.43) | SMN1; SMN2ALDH1A1RXFP1L3MBTL1HPGD | |
| SCHEMBL7044713 | 0.82 | RXFP1 (0.41) | SMN1; SMN2RXFP1KDM4EL3MBTL1HPGD | |
| SCHEMBL6551997 | 0.80 | PIN1 (0.45) | SMN1; SMN2ALDH1A1RXFP1KDM4EKMT2A | |
| SCHEMBL6553813 | 0.79 | MMP2 (0.48) | SMN1; SMN2ALDH1A1KDM4EL3MBTL1KMT2A | |
| SCHEMBL7048220 | 0.79 | L3MBTL1 (0.53) | SMN1; SMN2ALDH1A1RXFP1KDM4EL3MBTL1 | |
| SCHEMBL7045001 | 0.79 | SMN1; SMN2 (0.42) | SMN1; SMN2ALDH1A1RXFP1L3MBTL1HPGD | |
| SCHEMBL7044570 | 0.77 | NAAA (0.52) | ALDH1A1RXFP1KDM4EL3MBTL1HPGD | |
| SCHEMBL7047760 | 0.77 | LTB4R (0.49) | SMN1; SMN2ALDH1A1L3MBTL1KMT2ANPC1 | |
| SCHEMBL6552425 | 0.75 | LTB4R (0.57) | ALDH1A1KDM4EHPGDKMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | claimed |
| WO-2003007887-A2 | SUBSTITUTED IMIDAZOLES AS CANNABINOID RECEPTOR MODULATORS | MERCK & CO., INC. (US) | 2003-01-30 | — | — | WO | disclosed |