SCHEMBL7542998

SCHEMBL7542998

O=Cc1ccc(S(=O)(=O)OCc2ccccc2Cl)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.41
LMNA P02545 3/20 0.38
POLB P06746 2/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 5/20 0.37
PTPN1 P18031 2/20 0.37
TP53 P04637 1/20 0.36
F13A1 P00488 1/20 0.36
TGM2 P21980 1/20 0.36
TGM1 P22735 1/20 0.36
MAPT P10636 3/20 0.36
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
NPSR1 Q6W5P4 2/20 0.36
MAPK1 P28482 2/20 0.36
MEN1 O00255 1/20 0.36
HTT P42858 1/20 0.36
RAD52 P43351 1/20 0.36
KMT2A Q03164 1/20 0.36
HPGD P15428 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28243715 0.84 IDO1 (0.48) IDO1TDP1ALDH1A1MAPTKDM4E
SCHEMBL7542901 0.83 IDO1 (0.44) IDO1POLBALDH1A1TP53F13A1
SCHEMBL5870554 0.82 TP53 (0.53) IDO1LMNAPOLBALDH1A1TP53
SCHEMBL7535182 0.78 CA2 (0.49) ALDH1A1MAPTKDM4EL3MBTL1RAB9A
SCHEMBL7539097 0.78 NR4A2 (0.61) L3MBTL1MEN1KMT2AHPGDRAB9A
SCHEMBL8422956 0.75 NR4A2 (0.60) IDO1LMNAPOLBTDP1ALDH1A1
SCHEMBL7539915 0.74 ALDH1A1 (0.53) LMNAPOLBTDP1ALDH1A1MAPT
SCHEMBL7541893 0.72 IDO1 (0.37) IDO1LMNATDP1ALDH1A1MAPT
SCHEMBL20547082 0.71 HSD17B10 (0.45) IDO1LMNATDP1ALDH1A1KDM4E
SCHEMBL10962586 0.71 IDO1 (0.52) IDO1LMNAALDH1A1MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020094993-A1 Compositions for repelling crawling insects S.C. JOHNSON & SON, INC. 2002-07-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020094993-A1 Compositions for repelling crawling insects ACHE, DDT, GAP43 IDO1 2046/4885LMNA 4522/4885POLB 3165/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.