⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5872023 | 0.71 | NQO2 (0.30) | — | |
| SCHEMBL5726097 | 0.66 | CYP1A2 (0.36) | — | |
| SCHEMBL4179708 | 0.62 | CYP1A2 (0.34) | — | |
| SCHEMBL945494 | 0.60 | — | — | |
| SCHEMBL3404505 | 0.60 | ABCG2 (0.37) | — | |
| SCHEMBL144187 | 0.59 | IDO1 (0.32) | — | |
| SCHEMBL8172512 | 0.57 | NOTUM (0.36) | — | |
| SCHEMBL11229191 | 0.57 | KIF11 (0.31) | — | |
| SCHEMBL1801180 | 0.57 | TAS2R14 (0.30) | — | |
| SCHEMBL161183 | 0.57 | ABCG2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7071187-B2 | Naphthyridine derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2006-07-04 | — | — | US | disclosed |
| US-20040214853-A1 | Naphthyridine derivatives | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2004-10-28 | — | — | US | disclosed |
| EP-1426374-A1 | NAPHTHYRIDINE DERIVATIVE | OTSUKA PHARMACEUTICAL FACTORY, INC. (JP) | 2004-06-09 | — | — | EP | disclosed |