SCHEMBL1801180

SCHEMBL1801180

FC(F)(F)c1cc[c]c(Br)c1Br

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TAS2R14 Q9NYV8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18527601 0.77
SCHEMBL1068717 0.73 CA2 (0.34) TAS2R14
SCHEMBL526140 0.72 FABP4 (0.37)
SCHEMBL8084518 0.71
SCHEMBL6228844 0.69
SCHEMBL455888 0.68 EPHX2 (0.31)
SCHEMBL1844307 0.67
SCHEMBL1041748 0.67 TAS2R14 (0.46) TAS2R14
SCHEMBL147747 0.67
SCHEMBL25277776 0.65 NOTUM (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103261198-A 2-arylimidazo[1,2-]pyridazine, 2-phenylimidazo[1,2-a]pyridine, and 2-phenylimidazo[1,2-a]pyrazine derivatives JIANGSU HENGRUI MEDICINE CO 2013-08-21 CN disclosed
US-7951602-B2 Mass defect labeling and methods of use thereof UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 2011-05-31 US disclosed
US-20090061523-A1 MASS DEFECT LABELING AND METHODS OF USE THEREOF NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2009-03-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090061523-A1 MASS DEFECT LABELING AND METHODS OF USE THEREOF PTMS, SPPL2B, NPPA TAS2R14 3196/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.