Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 19/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1375990 | 0.77 | METAP2 (0.41) | METAP2METAP1GRIN2B | |
| SCHEMBL2951836 | 0.77 | NPC1 (0.41) | METAP2METAP1GRIN2B | |
| SCHEMBL19553769 | 0.77 | METAP2 (0.43) | METAP2METAP1GRIN2B | |
| Hydrochloric Acid SCHEMBL6821628 | 0.76 | KDM4E (0.42) | METAP2METAP1GRIN2B | |
| SCHEMBL10600439 | 0.76 | NPC1 (0.43) | METAP2METAP1GRIN2B | |
| SCHEMBL8781372 | 0.76 | — | — | |
| SCHEMBL10600599 | 0.73 | ADRA1A (0.49) | METAP2METAP1GRIN2B | |
| SCHEMBL9854786 | 0.72 | GRIN2B (0.49) | GRIN2B | |
| SCHEMBL12921851 | 0.72 | PARP1 (0.49) | METAP2METAP1GRIN2B | |
| SCHEMBL2388904 | 0.71 | GRIN2B (0.47) | GRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115433188-B | Preparation method of entecavir | 苏州东瑞制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-115433188-A | Preparation method of entecavir | 苏州东瑞制药有限公司 | 2022-12-06 | — | — | CN | disclosed |
| US-7153691-B2 | Method of identifying and assessing DNA euchromatin in biological cells for detecting disease, monitoring wellness, assessing bio-activity, and screening pharmacological agents | G6 SCIENCE CORP. (CA) | 2006-12-26 | — | — | US | disclosed |
| EP-1563093-A1 | METHOD OF IDENTIFYING AND ASSESSING DNA EUCHROMATIN FOR DETECTING DISEASE | G6 Science Corp. (CA) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004044237-A1 | METHOD OF IDENTIFYING AND ASSESSING DNA EUCHROMATIN FOR DETECTING DISEASE | G6 SCIENCE CORP. (CA) | 2004-05-27 | — | — | WO | disclosed |
| US-20040092026-A1 | Method of identifying and assessing DNA euchromatin in biological cells for detecting disease, monitoring wellness, assessing bio-activity, and screening pharmacological agents | G6 SCIENCE CORP. (CA) | 2004-05-13 | — | — | US | disclosed |
| WO-1998009964-A1 | IMPROVED PROCESS FOR PREPARING THE ANTIVIRAL AGENT [1S-(1α, 3α, 4β)]-2-AMINO-1,9-DIHYDRO-9-[4-HYDROXY-3-(HYDROXYMETHYL)-2-METHYLENECYCLOPENTYL]-6H-PURIN-6-ONE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1998-03-12 | — | — | WO | disclosed |
| CN-1030916-C | Process for preparing hydroxymethyl (methylenecyclopentyl) purines and pyrimidines | SQUIBB & SONS INC (US) | 1996-02-07 | — | — | CN | disclosed |
| US-5206244-A | Viricides | E. R. SQUIBB & SONS, INC. (US) | 1993-04-27 | — | — | US | disclosed |