Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.42 |
| ▸ | DPP4 | P27487 | 2/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1293117 | 0.82 | LMNA (0.50) | TAAR1LMNAAOC3TRPA1 | |
| SCHEMBL6736128 | 0.80 | LMNA (0.59) | LMNAADRA2AADRA2CHIF1AKDM4E | |
| SCHEMBL2192530 | 0.78 | DPP4 (0.56) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL8817244 | 0.78 | LMNA (0.46) | TAAR1LMNAAOC3TRPA1 | |
| SCHEMBL1168889 | 0.78 | ADRA2A (0.48) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL5872345 | 0.78 | ADRA2A (0.48) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL17504544 | 0.78 | ADRA2A (0.54) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL28342231 | 0.77 | HRH1 (0.55) | TAAR1LMNAADRA2AADRA2CHIF1A | |
| SCHEMBL9506306 | 0.77 | LMNA (0.45) | TAAR1LMNAAOC3CYP2D6TRPA1 | |
| SCHEMBL6745618 | 0.77 | DPP4 (0.58) | TAAR1LMNAADRA2AADRA2CHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7126028-B1 | Process for preparing chiral compounds | THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS (GB) | 2006-10-24 | — | — | US | disclosed |
| EP-1135349-A1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | UNIVERSITY OF DURHAM (GB) | 2001-09-26 | — | — | EP | disclosed |
| WO-2000034210-A1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | UNIVERSITY OF DURHAM (GB) | 2000-06-15 | — | — | WO | disclosed |