Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MIF | P14174 | 1/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1293117 | 0.84 | LMNA (0.50) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL8817244 | 0.80 | LMNA (0.46) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL2505449 | 0.78 | LMNA (0.56) | LMNATRPA1AOC3KMT2AMEN1 | |
| SCHEMBL5872340 | 0.77 | TAAR1 (0.43) | LMNATAAR1TRPA1AOC3CYP2D6 | |
| SCHEMBL12448782 | 0.76 | MIF (0.44) | AOC3MIFCYP2D6 | |
| SCHEMBL6546873 | 0.75 | SMN1; SMN2 (0.43) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL3627329 | 0.75 | LMNA (0.50) | LMNATAAR1TRPA1AOC3KMT2A | |
| SCHEMBL13619279 | 0.74 | NR3C1 (0.41) | LMNAKMT2AMEN1CYP2D6 | |
| SCHEMBL27504862 | 0.74 | ESR1 (0.50) | LMNATRPA1AOC3KMT2AMEN1 | |
| SCHEMBL22009966 | 0.73 | HKDC1 (0.52) | LMNATAAR1TRPA1AOC3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0440391-B1 | LUBRICANT COMPOSITIONS | NIPPON OIL CO. LTD. (JP) | 1993-08-18 | — | — | EP | disclosed |
| US-5194168-A | Base oil containing particles of crosslinked polybutadiene | NIPPON OIL CO., LTD. (JP) | 1993-03-16 | — | — | US | disclosed |
| EP-0440391-A1 | Lubricant compositions | NIPPON OIL CO. LTD. (JP) | 1991-08-07 | — | — | EP | disclosed |