Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.41 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.41 |
| ▸ | RNF4 | P78317 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL855736 | 0.91 | — | — | |
| SCHEMBL855625 | 0.84 | SOAT2 (0.52) | UBE2MDCUN1D1SOAT2SOAT1 | |
| SCHEMBL854468 | 0.83 | RXRA (0.48) | — | |
| SCHEMBL856126 | 0.82 | STAT3 (0.43) | — | |
| SCHEMBL881081 | 0.82 | SOAT2 (0.55) | UBE2MDCUN1D1SOAT2SOAT1 | |
| SCHEMBL10189418 | 0.82 | SOAT2 (0.48) | UBE2MDCUN1D1SOAT2SOAT1 | |
| SCHEMBL881086 | 0.82 | UBE2M (0.40) | UBE2MDCUN1D1SOAT2SOAT1 | |
| SCHEMBL853667 | 0.81 | UBE2M (0.49) | UBE2MDCUN1D1SOAT2SOAT1 | |
| SCHEMBL855121 | 0.81 | BCHE (0.47) | — | |
| SCHEMBL855132 | 0.81 | SOAT2 (0.44) | SOAT2SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7105567-B2 | 3-substituted urea derivatives and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2006-09-12 | — | — | US | disclosed |
| US-20030207939-A1 | Novel 3-substituted urea derivatives and medicinal use thereof | MITSUBISHI PHARMA CORPORATION (JP) | 2003-11-06 | — | — | US | disclosed |
| EP-1308438-A1 | 3-SUBSTITUTED UREA DERIVATIVES AND MEDICINAL USE THEREOF | Mitsubishi Pharma Corporation (JP) | 2003-05-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030207939-A1 | Novel 3-substituted urea derivatives and medicinal use thereof | C5AR1, C5AR2, C3AR1 | UBE2M 1436/4885DCUN1D1 1246/4885SOAT2 3181/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.