Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
| ▸ | MMP2 | P08253 | 1/20 | 0.30 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
| ▸ | MMP8 | P22894 | 1/20 | 0.30 |
| ▸ | MMP13 | P45452 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127906 | 0.72 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL576254 | 0.69 | ALDH1A1 (0.35) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL3189616 | 0.68 | MMP1 (0.34) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL2204380 | 0.67 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL2058155 | 0.67 | CA1 (0.33) | CA1CA2 | |
| SCHEMBL6261329 | 0.67 | CA2 (0.42) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL155905 | 0.67 | MMP1 (0.40) | CA1CA2MMP1MMP2MMP9 | |
| Trifluoromethanesulfonic Acid SCHEMBL1131470 | 0.67 | ALDH1A1 (0.33) | — | |
| Trifluoromethanesulfonic Acid SCHEMBL2239043 | 0.67 | ALDH1A1 (0.33) | CA1CA2MMP1MMP2MMP9 | |
| SCHEMBL31686017 | 0.66 | CA2 (0.37) | CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7098282-B2 | Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof | NOVICKY NICK | 2006-08-29 | — | — | US | disclosed |
| US-20050176907-A1 | Fluorosulfone-silicone hydrogel, RGP contact lenses, optical medical devices and compositions thereof | NOVICKY NICK (CA) | 2005-08-11 | — | — | US | disclosed |
| EP-1455201-A1 | Fluorosulfone-silicone hydrogel RGP contact lenses, optical medical devices and compositions thereof | Novicky, Nick N. (CA) | 2004-09-08 | — | — | EP | disclosed |