Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 15/20 | 0.60 |
| ▸ | CTSB | P07858 | 15/20 | 0.60 |
| ▸ | CTSS | P25774 | 14/20 | 0.60 |
| ▸ | CTSK | P43235 | 9/20 | 0.60 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4698985 | 0.90 | CTSL (0.57) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4703668 | 0.89 | CTSL (0.75) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4698975 | 0.87 | CTSL (0.72) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4702191 | 0.87 | CTSL (0.80) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4700767 | 0.85 | CTSL (0.58) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4698891 | 0.79 | CTSL (0.61) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4699311 | 0.79 | CTSS (0.61) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4699998 | 0.79 | CTSK (0.57) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4702312 | 0.78 | CTSB (0.51) | CTSLCTSBCTSSCTSK | |
| SCHEMBL4700189 | 0.78 | CTSL (0.57) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012075-B2 | Cathepsin cysteine protease inhibitors | MERCK & CO., INC. (US) | 2006-03-14 | — | — | US | claimed |