SCHEMBL5872563

SCHEMBL5872563

Clc1ccc2c(c1)N=CC2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTR2A P28223 2/20 0.36
HTR2C P28335 2/20 0.36
HTR2B P41595 2/20 0.36
ACHE P22303 1/20 0.36
PNMT P11086 1/20 0.34
HTR3A P46098 2/20 0.34
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34
HTR3D Q70Z44 1/20 0.34
HTR3C Q8WXA8 1/20 0.34
HTR5A P47898 2/20 0.33
CTSD P07339 1/20 0.33
CMA1 P23946 1/20 0.33
AHR P35869 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
MAPT P10636 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27952697 0.83 HTR2A (0.36) HTR2AHTR2CHTR2BACHEPNMT
SCHEMBL10969836 0.79 HTR2A (0.38) HTR2AHTR2CHTR2BACHEPNMT
SCHEMBL29531917 0.79 HTR2A (0.38) HTR2AHTR2CHTR2BACHEPNMT
SCHEMBL17177458 0.74
SCHEMBL255506 0.74 HTR5A (0.34) ACHEHTR5AMEN1KMT2AKDM4E
SCHEMBL5636813 0.72 S100A4 (0.41) ACHECMA1AHRMEN1KMT2A
SCHEMBL3652467 0.71 HTR2A (0.38) HTR2AHTR2CHTR2BACHEPNMT
SCHEMBL18618028 0.69 TRPA1 (0.36) CTSDKDM4ENPC1MAPTRAB9A
SCHEMBL7038650 0.69 TRPA1 (0.44) PNMTKDM1A
SCHEMBL138109 0.69 ALDH1A1 (0.36) MEN1KMT2ANPC1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0881284-A1 Culture medium for the specific detection of enterobacteries, procedure for its obtention and use Société La Biochimie Appliquée - SO.LA.BI.A. (FR) 1998-12-02 EP claimed
US-11505816-B2 Medium for detecting Staphylococcus aureus, sheet for detecting S. aureus comprising same, and method for detecting S. aureus using same KIKKOMAN CORPORATION (JP) 2022-11-22 US disclosed
CN-108603215-B Culture medium for detecting staphylococcus aureus, staphylococcus aureus detection sheet having the same, and method for detecting staphylococcus aureus using the same 龟甲万株式会社 2022-10-14 CN disclosed
US-20210017566-A1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS, SHEET FOR DETECTING S. AUREUS COMPRISING SAME, AND METHOD FOR DETECTING S. AUREUS USING SAME KIKKOMAN CORPORATION (JP) 2021-01-21 US disclosed
US-10822632-B2 Medium for detecting Staphylococcus aureus, sheet for detecting S. aureus comprising same, and method for detecting S. aureus using same DAI NIPPON PRINTING CO., LTD. (JP) 2020-11-03 US disclosed
EP-3409784-B1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS DAINIPPON PRINTING CO LTD (JP) 2020-10-07 EP disclosed
US-20190024136-A1 MEDIUM FOR DETECTING STAPHYLOCOCCUS AUREUS, SHEET FOR DETECTING S. AUREUS COMPRISING SAME, AND METHOD FOR DETECTING S. AUREUS USING SAME KIKKOMAN CORPORATION (JP) 2019-01-24 US disclosed
EP-3409784-A1 MEDIUM FOR DETECTINGSTAPHYLOCOCCUS AUREUS Dai Nippon Printing Co., Ltd. (JP) 2018-12-05 EP disclosed
US-20140113327-A1 BIOCHEMICAL SENSOR FOR QUANTITATIVE SIMULTANEOUS MULTI-SPECIES BACTERIA DETECTION IN SITU Environmental Technology Solutiions LLC (US) 2014-04-24 US disclosed
US-20130260417-A1 BIOCHEMICAL SENSOR FOR QUANTITATIVE SIMULTANEOUS MULTI-SPECIES BACTERIA DETECTION IN SITU ENVIRONMENTAL TECHNOLOGY SOLUTIONS LLC (US) 2013-10-03 US disclosed
US-7033777-B2 Method for detecting cockroach allergens and determining total allergen level TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) 2006-04-25 US disclosed
US-20030180826-A1 Method and test kit for detecting cockroach allergens and determining total allergen level TEMPLE UNIVERSITY OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION 2003-09-25 US disclosed
EP-0881284-A1 Culture medium for the specific detection of enterobacteries, procedure for its obtention and use Société La Biochimie Appliquée - SO.LA.BI.A. (FR) 1998-12-02 EP disclosed