Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 1/20 | 0.42 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 4/20 | 0.41 |
| ▸ | RXRA | P19793 | 3/20 | 0.35 |
| ▸ | RXRB | P28702 | 3/20 | 0.35 |
| ▸ | RXRG | P48443 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.34 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TYR | P14679 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5873304 | 0.80 | KIF11 (0.44) | AKR1C2AKR1C1KIF11RXRARXRB | |
| SCHEMBL5873293 | 0.76 | KIF11 (0.39) | AKR1C2AKR1C1KIF11RXRARXRB | |
| SCHEMBL23319641 | 0.73 | KIF11 (0.61) | AKR1C2AKR1C1KIF11RXRARXRB | |
| SCHEMBL4322427 | 0.73 | KIF11 (0.61) | AKR1C2AKR1C1KIF11RXRARXRB | |
| SCHEMBL14666772 | 0.72 | CNR1 (0.51) | AKR1C2AKR1C1KIF11RXRARXRB | |
| SCHEMBL16908378 | 0.71 | MMP3 (0.42) | KIF11TSHRALDH1A1CA12CA9 | |
| SCHEMBL5134086 | 0.71 | KIF11 (0.48) | AKR1C2AKR1C1KIF11RXRARXRB | |
| SCHEMBL31156291 | 0.71 | AHR (0.58) | AKR1C2AKR1C1KIF11RXRARXRB | |
| SCHEMBL3423876 | 0.71 | KIF11 (0.70) | KIF11TSHRXDHMITFALDH1A1 | |
| SCHEMBL26915 | 0.71 | KIF11 (0.70) | KIF11TSHRXDHMITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056996-B2 | Productivity catalysts and microstructure control | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-06 | — | — | US | disclosed |
| US-20040127658-A1 | Productivity catalysts and microstructure control | EASTMAN CHEMICAL COMPANY | 2004-07-01 | — | — | US | disclosed |
| US-20040077809-A1 | Productivity catalysts and microstructure control | EASTMAN CHEMICAL COMPANY | 2004-04-22 | — | — | US | disclosed |
| EP-1404723-A2 | OLEFIN POLYMERIZATION PROCESSES USING SUPPORTED CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2004-04-07 | — | — | EP | disclosed |
| EP-1351997-A2 | IMPROVED PRODUCTIVITY CATALYSTS AND MICROSTRUCTURE CONTROL | EASTMAN CHEMICAL COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| US-6605677-B2 | Group 8-10 transition metal based supported catalyst where the support is treated with a pore-filling agent; improved the catalyst productivity in the presence of hydrogen | EASTMAN CHEMICAL COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-20020091210-A1 | Olefin polymerization processes using supported catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-07-11 | — | — | US | disclosed |
| US-20020065192-A1 | Productivity catalysts and microstructure control | MACKENZIE PETER BORDEN (US) | 2002-05-30 | — | — | US | disclosed |
| WO-2002036641-A2 | IMPROVED PRODUCTIVITY CATALYSTS AND MICROSTRUCTURE CONTROL | EASTMAN CHEMICAL COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002036642-A2 | OLEFIN POLYMERIZATION PROCESSES USING SUPPORTED CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077809-A1 | Productivity catalysts and microstructure control | MYB, ST3GAL3, FASN | AKR1C2 3593/4885AKR1C1 3837/4885KIF11 357/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.