Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 5/20 | 0.44 |
| ▸ | DHODH | Q02127 | 1/20 | 0.43 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | RXRB | P28702 | 4/20 | 0.40 |
| ▸ | RXRG | P48443 | 2/20 | 0.40 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.40 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.40 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ASIC1 | P78348 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4648856 | 0.84 | RXRA (0.41) | KIF11RXRARXRBRXRGCYP2C9 | |
| SCHEMBL28102065 | 0.84 | DHODH (0.54) | KIF11DHODHHSD17B2RXRARXRB | |
| SCHEMBL26771321 | 0.84 | DHODH (0.54) | KIF11DHODHHSD17B2RXRARXRB | |
| SCHEMBL5873284 | 0.84 | ALDH1A1 (0.47) | KIF11DHODHALOX5 | |
| SCHEMBL3421942 | 0.82 | KIF11 (0.59) | KIF11DHODHHSD17B2RXRARXRB | |
| SCHEMBL128222 | 0.82 | KIF11 (0.59) | KIF11DHODHHSD17B2RXRARXRB | |
| SCHEMBL456946 | 0.82 | ALDH1A1 (0.50) | CYP19A1ALOX5 | |
| SCHEMBL27957889 | 0.81 | KIF11 (0.41) | KIF11DHODHHSD17B2RXRARXRB | |
| SCHEMBL5873300 | 0.80 | AKR1C2 (0.42) | KIF11DHODHRXRARXRBRXRG | |
| Ethane SCHEMBL27903947 | 0.80 | KIF11 (0.57) | KIF11DHODHHSD17B2RXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7056996-B2 | Productivity catalysts and microstructure control | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2006-06-06 | — | — | US | disclosed |
| US-6946532-B2 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY (US) | 2005-09-20 | — | — | US | disclosed |
| US-20050090381-A1 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY (US) | 2005-04-28 | — | — | US | disclosed |
| US-6844446-B2 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY (US) | 2005-01-18 | — | — | US | disclosed |
| US-20040127658-A1 | Productivity catalysts and microstructure control | EASTMAN CHEMICAL COMPANY | 2004-07-01 | — | — | US | disclosed |
| US-20040077809-A1 | Productivity catalysts and microstructure control | EASTMAN CHEMICAL COMPANY | 2004-04-22 | — | — | US | disclosed |
| EP-1404723-A2 | OLEFIN POLYMERIZATION PROCESSES USING SUPPORTED CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2004-04-07 | — | — | EP | disclosed |
| US-20030228978-A1 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | EASTMAN CHEMICAL COMPANY | 2003-12-11 | — | — | US | disclosed |
| EP-1351997-A2 | IMPROVED PRODUCTIVITY CATALYSTS AND MICROSTRUCTURE CONTROL | EASTMAN CHEMICAL COMPANY (US) | 2003-10-15 | — | — | EP | disclosed |
| US-6605677-B2 | Group 8-10 transition metal based supported catalyst where the support is treated with a pore-filling agent; improved the catalyst productivity in the presence of hydrogen | EASTMAN CHEMICAL COMPANY | 2003-08-12 | — | — | US | disclosed |
| US-6579823-B2 | Group 8-10 metal complex comprising a bidentate or variable denticity ligand; polymerization of olefins | EASTMAN CHEMICAL COMPANY | 2003-06-17 | — | — | US | disclosed |
| EP-1317490-A1 | CATALYSTS CONTAINING PER-ORTHO ARYL SUBSTITUTED ARYL OR HETEROARYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2003-06-11 | — | — | EP | disclosed |
| US-20020091210-A1 | Olefin polymerization processes using supported catalysts | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-07-11 | — | — | US | disclosed |
| US-20020065192-A1 | Productivity catalysts and microstructure control | MACKENZIE PETER BORDEN (US) | 2002-05-30 | — | — | US | disclosed |
| WO-2002036641-A2 | IMPROVED PRODUCTIVITY CATALYSTS AND MICROSTRUCTURE CONTROL | EASTMAN CHEMICAL COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
| WO-2002036642-A2 | OLEFIN POLYMERIZATION PROCESSES USING SUPPORTED CATALYSTS | EASTMAN CHEMICAL COMPANY (US) | 2002-05-10 | — | — | WO | disclosed |
| US-20020049135-A1 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | E. I. DU PONT DE NEMOURS AND COMPANY | 2002-04-25 | — | — | US | disclosed |
| WO-2002022694-A1 | CATALYSTS CONTAINING PER-ORTHO ARYL SUBSTITUTED ARYL OR HETEROARYL SUBSTITUTED NITROGEN DONORS | EASTMAN CHEMICAL COMPANY (US) | 2002-03-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077809-A1 | Productivity catalysts and microstructure control | MYB, ST3GAL3, FASN | KIF11 357/4885DHODH 3257/4885HSD17B2 2026/4885 |
| US-20050090381-A1 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | NOX3, AHR, POF1B | KIF11 2784/4885DHODH 560/4885HSD17B2 3520/4885 |
| US-20030228978-A1 | Catalysts containing per-ortho aryl substituted aryl or heteroaryl substituted nitrogen donors | NOX3, AOC3, AHR | KIF11 2681/4885DHODH 582/4885HSD17B2 3457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.