Sugi Predict

Sugi Predict / Compounds / SCHEMBL5873452

SCHEMBL5873452

SCHEMBL5873452

CC(O)C(c1ccccc1)c1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ LMNA P02545 4/20 0.52
▸ ADRA2C P18825 2/20 0.52
▸ KDM4E B2RXH2 2/20 0.52
▸ ADRA2A P08913 1/20 0.52
▸ HIF1A Q16665 1/20 0.52
▸ ALDH1A1 P00352 2/20 0.50
▸ TSHR P16473 2/20 0.48
▸ CHRM2 P08172 1/20 0.48
▸ ADRA1A P35348 1/20 0.48
▸ RGS12 O14924 1/20 0.48
▸ GLA P06280 1/20 0.48
▸ CYP3A4 P08684 1/20 0.48
▸ CYP2D6 P10635 1/20 0.48
▸ CYP2C9 P11712 1/20 0.48
▸ PKM P14618 1/20 0.48
▸ ALOX15 P16050 1/20 0.48
▸ ALOX12 P18054 1/20 0.48
▸ NFKB1 P19838 1/20 0.48
▸ HTR2A P28223 1/20 0.48
▸ CYP2C19 P33261 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10368322 1.00 LMNA (0.52) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL27870659 1.00 LMNA (0.52) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL5700715 0.89 ESR1 (0.50) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL15617630 0.89 LMNA (0.46) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL15617669 0.87 SLC6A2 (0.49) LMNAADRA2CKDM4EADRA2AHIF1A
Nitric Acid SCHEMBL9875242 0.85 LMNA (0.41) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL1668309 0.84 LMNA (0.48) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL19029385 0.83 SMN1; SMN2 (0.44) LMNAADRA2CKDM4EADRA2AHIF1A
SCHEMBL15617631 0.83 ACP3 (0.56) ALDH1A1TSHRCYP3A4PKMHSD17B10
SCHEMBL2185727 0.82 ALDH1A1 (0.46) LMNAADRA2CKDM4EADRA2AHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3261640-A1 5HT AGONISTS FOR TREATING DISORDERS The Regents of The University of California (US) 2018-01-03 — — EP claimed
WO-2016138138-A1 5HT AGONISTS FOR TREATING DISORDERS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2016-09-01 — — WO claimed
US-6989052-B1 Phase change ink printing process XEROX CORPORATION (US) 2006-01-24 — — US claimed
US-20060004123-A1 PHASE CHANGE INK PRINTING PROCESS XEROX CORPORATION 2006-01-05 — — US claimed
EP-0674232-B1 Recording sheets XEROX CORP (US) 2000-05-31 — — EP claimed
US-5663022-A Recording sheets XEROX CORPORATION (US) 1997-09-02 — — US claimed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 — — EP claimed
US-20240423207-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC (US) 2024-12-26 — — US disclosed
US-12114660-B2 Picolinamide compounds with fungicidal activity CORTEVA AGRISCIENCE LLC (US) 2024-10-15 — — US disclosed
US-20230371516-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC (US) 2023-11-23 — — US disclosed
US-11751568-B2 Picolinamide compounds with fungicidal activity CORTEVA AGRISCIENCE LLC (US) 2023-09-12 — — US disclosed
US-20220159962-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY CORTEVA AGRISCIENCE LLC (US) 2022-05-26 — — US disclosed
US-11284620-B2 Picolinamide compounds with fungicidal activity CORTEVA AGRISCIENCE LLC (US) 2022-03-29 — — US disclosed
US-5663022-A Recording sheets XEROX CORPORATION (US) 1997-09-02 — — US disclosed
EP-0674232-A2 Recording sheets XEROX CORPORATION (US) 1995-09-27 — — EP disclosed
US-5451466-A Electrophotographic use, reduced heat and energy required for toner fusion, styrene copolymer, indan or derivative XEROX CORPORATION (US) 1995-09-19 — — US disclosed
CN-1064481-A Hydrazone compound, its preparation method reach the pesticide composition that it is prepared useful intermediate and contains these materials ISHIHARA SANGYO KAISHA (JP) 1992-09-16 — — CN disclosed
US-5049694-A Cardiovascular disorders CEDONA PHARMACEUTICALS B.V. (NL) 1991-09-17 — — US disclosed
EP-0359335-A2 Pharmaceutical composition having relaxing activity which contains a nitrate ester as active substance CEDONA PHARMACEUTICALS B.V. (NL) 1990-03-21 — — EP disclosed
US-3953494-A FORMING ACIDS AND ESTERS SOUTHERN ILLINOIS UNIVERSITY FOUNDATION (US) 1976-04-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220159962-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY PFAS, CASP2, CYP1A2 LMNA 3069/4885ADRA2C 4054/4885KDM4E 2492/4885
US-20230371516-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY PFAS, CASP2, CYP1A2 LMNA 3069/4885ADRA2C 4054/4885KDM4E 2492/4885
US-11751568-B2 Picolinamide compounds with fungicidal activity PFAS, CASP2, CYP1A2 LMNA 3069/4885ADRA2C 4054/4885KDM4E 2492/4885
US-12114660-B2 Picolinamide compounds with fungicidal activity PFAS, CASP2, CYP1A2 LMNA 3069/4885ADRA2C 4054/4885KDM4E 2492/4885
US-11284620-B2 Picolinamide compounds with fungicidal activity PFAS, CASP2, CYP1A2 LMNA 3069/4885ADRA2C 4054/4885KDM4E 2492/4885
US-20240423207-A1 PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY PFAS, CASP2, CYP1A2 LMNA 3069/4885ADRA2C 4054/4885KDM4E 2492/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.