Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | FNTA | P49354 | 1/20 | 0.49 |
| ▸ | FNTB | P49356 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | CTSL | P07711 | 1/20 | 0.48 |
| ▸ | CTSB | P07858 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 1/20 | 0.48 |
| ▸ | CTSK | P43235 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253758 | 0.97 | PREP (0.60) | PREPALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8249773 | 0.96 | PREP (0.59) | PREPALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL11263011 | 0.94 | PREP (0.59) | PREPALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL7159251 | 0.94 | PREP (0.59) | PREPALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL27795955 | 0.90 | PREP (0.56) | PREPALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL5873672 | 0.89 | GAA (0.55) | PREPALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL7509784 | 0.88 | PREP (0.54) | PREPALDH1A1LMNASMN1; SMN2GAA | |
| SCHEMBL7683566 | 0.88 | GAA (0.54) | PREPALDH1A1L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL4075221 | 0.87 | SIGMAR1 (0.57) | PREPL3MBTL1HTTKMT2ASIGMAR1 | |
| SCHEMBL2586953 | 0.85 | L3MBTL1 (0.61) | PREPALDH1A1L3MBTL1SMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0764151-A2 | PURIFICATION OF SERINE PROTEASE AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1997-03-26 | — | — | EP | disclosed |
| WO-1995034538-A2 | PURIFICATION OF SERINE PROTEASES AND SYNTHETIC INHIBITORS THEREOF | UNIVERSITAIRE INSTELLING ANTWERPEN (BE) | 1995-12-21 | — | — | WO | disclosed |