Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | DPP4 | P27487 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8253758 | 0.99 | PREP (0.60) | PREPALDH1A1RAB9AOPRK1SMN1; SMN2 | |
| SCHEMBL8750837 | 0.96 | PREP (0.60) | PREPALDH1A1RAB9AOPRK1SMN1; SMN2 | |
| SCHEMBL7159251 | 0.93 | PREP (0.59) | PREPALDH1A1OPRK1SMN1; SMN2LMNA | |
| SCHEMBL11263011 | 0.93 | PREP (0.59) | PREPALDH1A1OPRK1SMN1; SMN2LMNA | |
| SCHEMBL27795955 | 0.89 | PREP (0.56) | PREPALDH1A1OPRK1SMN1; SMN2LMNA | |
| SCHEMBL5873672 | 0.88 | GAA (0.55) | PREPALDH1A1OPRK1SMN1; SMN2LMNA | |
| SCHEMBL7683566 | 0.86 | GAA (0.54) | PREPALDH1A1OPRK1SMN1; SMN2LMNA | |
| SCHEMBL7509784 | 0.86 | PREP (0.54) | PREPALDH1A1OPRK1SMN1; SMN2LMNA | |
| SCHEMBL2586953 | 0.84 | L3MBTL1 (0.61) | PREPALDH1A1RAB9ASMN1; SMN2NPC1 | |
| SCHEMBL4075221 | 0.84 | SIGMAR1 (0.57) | PREPL3MBTL1MEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3963728-A | ACYLATION OF NITROGEN CONTAINING COMPOUNDS USING ESTERS | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-06-15 | — | — | US | claimed |
| WO-2006127702-A2 | ANALOGS OF GLYCYL-PROLYL-GLUTAMATE | NEUREN PHARMACEUTICALS LIMITED (NZ) | 2006-11-30 | — | — | WO | disclosed |
| US-RE29369-E | AMIDE PRODUCT, SALTS OF HYDROXY-SUBSTITUTED PYRIDINE COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1977-08-23 | — | — | US | disclosed |
| US-4043992-A | Method for preparing acylated products | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1977-08-23 | — | — | US | disclosed |
| US-3963728-A | ACYLATION OF NITROGEN CONTAINING COMPOUNDS USING ESTERS | KYOWA HAKKO KOGYO CO., LTD. (JA) | 1976-06-15 | — | — | US | disclosed |