Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5874043 | 0.98 | CYP2D6 (0.42) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL21927029 | 0.90 | ALDH1A1 (0.43) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| Hydrochloric Acid SCHEMBL5874113 | 0.87 | CYP2D6 (0.40) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL6997616 | 0.82 | SLC6A2 (0.42) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL3892446 | 0.81 | MAOA (0.50) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL27381576 | 0.81 | CYP2D6 (0.40) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL11972618 | 0.78 | DPP4 (0.48) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL20777704 | 0.78 | DPP4 (0.53) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 | |
| SCHEMBL20978162 | 0.78 | ALDH1A1 (0.43) | CYP2D6SLC6A2SLC6A4SLC6A3OPRM1 | |
| SCHEMBL6803003 | 0.77 | DPP4 (0.52) | SLC6A2SLC6A4SLC6A3OPRM1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7012144-B2 | Quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2006-03-14 | — | — | US | disclosed |
| US-20030130302-A1 | Quinolone carboxylic acid derivatives | KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) | 2003-07-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030130302-A1 | Quinolone carboxylic acid derivatives | CYCS, CBR3, HCCS | CYP2D6 37/4885SLC6A2 3327/4885SLC6A4 3075/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.