Cadaverine Tartrate

Cadaverine Tartrate

SCHEMBL5874100

C1CCNCC1.C1CCNCC1.O=C(O)C(O)C(O)C(=O)O

nearest known ligand 0.53

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GBA1 known ✓ P04062 1/20 0.41
GABRA1 known ✓ P14867 1/20 0.33
GABRB1 known ✓ P18505 1/20 0.33
GABRG2 known ✓ P18507 1/20 0.33
TSHR P16473 5/20 0.53
ALDH1A1 P00352 1/20 0.47
NFKB1 P19838 1/20 0.39
CYP2C19 P33261 1/20 0.39
CA2 P00918 1/20 0.34
CHKA P35790 1/20 0.34
CPN1 P15169 3/20 0.33
CPB2 Q96IY4 3/20 0.33
SLC6A1 P30531 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
PMP22 Q01453 2/20 0.33
LMNA P02545 2/20 0.33
SLC6A11 P48066 1/20 0.33
CXCR4 P61073 1/20 0.33
GABRP O00591 1/20 0.33
GABRD O14764 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tartaric Acid SCHEMBL29930272 1.00 TSHR (0.53) TSHRALDH1A1GBA1NFKB1CYP2C19
Cadaverine Tartrate SCHEMBL5874109 1.00 TSHR (0.53) TSHRALDH1A1GBA1NFKB1CYP2C19
Cadaverine Tartrate SCHEMBL29643329 1.00 TSHR (0.53) TSHRALDH1A1GBA1NFKB1CYP2C19
Cadaverine Tartrate SCHEMBL2786076 0.97 TSHR (0.56) TSHRALDH1A1GBA1NFKB1CYP2C19
Cadaverine Tartrate SCHEMBL31315681 0.97 TSHR (0.56) TSHRALDH1A1GBA1NFKB1CYP2C19
Tartaric Acid SCHEMBL30597927 0.95 TSHR (0.53) TSHRALDH1A1GBA1NFKB1CYP2C19
Cadaverine Tartrate SCHEMBL27710408 0.91 TSHR (0.43) TSHRALDH1A1GBA1NFKB1CYP2C19
Cadaverine Tartrate SCHEMBL8734652 0.89 TSHR (0.67) TSHRALDH1A1GBA1NFKB1CYP2C19
Cadaverine Tartrate SCHEMBL5874937 0.86 TSHR (0.62) TSHRGBA1NFKB1CYP2C19CPN1
Cadaverine Tartrate SCHEMBL1642932 0.86 TSHR (0.62) TSHRGBA1NFKB1CYP2C19CPN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
EP-3518878-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION Henkel AG & Co. KGaA (DE) 2019-08-07 EP disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 GBA1 4772/4885GABRA1 3244/4885GABRB1 3591/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK GBA1 4755/4885GABRA1 4266/4885GABRB1 4254/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA GBA1 4733/4885GABRA1 3350/4885GABRB1 3424/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 GBA1 4766/4885GABRA1 1431/4885GABRB1 1537/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.