Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Piperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR known ✓ | P35968 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | FDPS | P14324 | 4/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP3 | P08254 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Piperidine SCHEMBL5874242 | 1.00 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL9857707 | 1.00 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Piperidine SCHEMBL1242732 | 1.00 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Azepane SCHEMBL7914286 | 0.97 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Pyrrolidine SCHEMBL23354581 | 0.97 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Pyrrolidine SCHEMBL29601650 | 0.97 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Pyrrolidine SCHEMBL28575035 | 0.97 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA | |
| Pyrrolidine SCHEMBL28409763 | 0.93 | ALDH1A1 (0.50) | ALDH1A1CXCR4SMN1; SMN2FDPSMAPT | |
| Phosphoric Acid SCHEMBL28853896 | 0.89 | — | — | |
| Piperidine SCHEMBL6064824 | 0.89 | ALDH1A1 (0.47) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930468-A | Synthesis method of medical cyanoacrylate adhesive with low formaldehyde residue | 山东禹王和天下新材料有限公司 | 2025-05-06 | — | — | CN | claimed |
| EP-3822259-A1 | METHOD FOR SYNTHESIZING VALSARTAN | Zhejiang Huahai Pharmaceutical Co., Ltd. (CN) | 2021-05-19 | — | — | EP | claimed |
| CN-107922448-A | A kind of deuterated thieno piperidine derivative, preparation method and applications | 江苏天士力帝益药业有限公司 | 2018-04-17 | — | — | CN | claimed |
| CN-107698620-A | A kind of deuterated thieno piperidine derivative, preparation method and applications | 江苏天士力帝益药业有限公司 | 2018-02-16 | — | — | CN | claimed |
| CN-105541664-B | A kind of method for synthesizing cyanoacrylate | 潍坊同业化学有限公司 | 2018-01-30 | — | — | CN | claimed |
| CN-104447867-B | A kind of thieno piperidine derivative, preparation method and applications | 江苏天士力帝益药业有限公司 | 2017-12-26 | — | — | CN | claimed |
| CN-105805426-B | Pipeline runs through device | 上海火克新材料有限公司 | 2017-10-27 | — | — | CN | claimed |
| CN-105541664-A | Method for synthesizing cyanoacrylate | WEIFANG TONGYE CHEMICAL CO LTD | 2016-05-04 | — | — | CN | claimed |
| EP-0436301-B1 | Crystal-polymer matrix composites | BRITISH TECH GROUP (GB) | 1995-03-15 | — | — | EP | claimed |
| US-5167888-A | In situ growth of organic and/or inorganic crystals in a polymer matrix by using temperature gradient zone melting technique | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1992-12-01 | — | — | US | claimed |
| EP-0436301-A2 | Crystal-polymer matrix composites | BTG INTERNATIONAL LIMITED (GB) | 1991-07-10 | — | — | EP | claimed |
| EP-4676747-A1 | METHODS AND USES FOR CONTROLLING DOT SIZE | Ricoh Company, Ltd. (JP) | 2026-01-14 | — | — | EP | disclosed |
| CN-119930468-A | Synthesis method of medical cyanoacrylate adhesive with low formaldehyde residue | 山东禹王和天下新材料有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-119606969-A | Pharmaceutical composition and application thereof | 九华华源药业(桂林)有限公司 | 2025-03-14 | — | — | CN | disclosed |
| WO-2024221494-A1 | CATALYST, PREPARATION METHOD THEREFOR, AND USE THEREOF | 上海凯赛生物技术股份有限公司 | 2024-10-31 | — | — | WO | disclosed |
| EP-0436301-B1 | Crystal-polymer matrix composites | BRITISH TECH GROUP (GB) | 1995-03-15 | — | — | EP | disclosed |
| CN-1022244-C | Tetrazole excitatory amino acid receptor antagonists | LILLY CO ELI (US) | 1993-09-29 | — | — | CN | disclosed |
| US-5167888-A | In situ growth of organic and/or inorganic crystals in a polymer matrix by using temperature gradient zone melting technique | THE BRITISH PETROLEUM COMPANY P.L.C. (GB) | 1992-12-01 | — | — | US | disclosed |
| EP-0436301-A2 | Crystal-polymer matrix composites | BTG INTERNATIONAL LIMITED (GB) | 1991-07-10 | — | — | EP | disclosed |
| CN-1035114-A | TETRAZOLE EXCITATORY AMINO ACID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 1989-08-30 | — | — | CN | disclosed |