Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Pyrrolidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR known ✓ | P35968 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PDE4A | P27815 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CHKA | P35790 | 1/20 | 0.31 |
| ▸ | RGS12 | O14924 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.30 |
| ▸ | GABRR2 | P28476 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | BLM | P54132 | 1/20 | 0.30 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.30 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL29601650 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Pyrrolidine SCHEMBL23354581 | 1.00 | ALDH1A1 (0.53) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Piperidine SCHEMBL5874248 | 0.97 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Pyrrolidine SCHEMBL28409763 | 0.97 | ALDH1A1 (0.50) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Piperidine SCHEMBL1242732 | 0.97 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Piperidine SCHEMBL9857707 | 0.97 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Piperidine SCHEMBL5874242 | 0.97 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2HIF1AMAPT | |
| Azepane SCHEMBL7914286 | 0.94 | ALDH1A1 (0.56) | ALDH1A1CXCR4SMN1; SMN2FDPSCA2 | |
| Phosphoric Acid SCHEMBL28853896 | 0.93 | — | — | |
| Pyrrolidine SCHEMBL29131986 | 0.91 | ALDH1A1 (0.44) | ALDH1A1CXCR4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113543706-B | Electrode comprising a conductive acrylate-based pressure sensitive adhesive | 汉高股份有限及两合公司 | 2024-07-23 | — | — | CN | claimed |
| CN-118235027-A | Ion conductive composition for thermal sensor | 汉高股份有限及两合公司 | 2024-06-21 | — | — | CN | claimed |
| CN-115989294-A | Dry stimulating electrode | 汉高股份有限及两合公司 | 2023-04-18 | — | — | CN | claimed |
| CN-114487198-A | Relative quantitative method of phosphorylated peptide | 江汉大学 | 2022-05-13 | — | — | CN | claimed |
| CN-113557281-A | Dry electrode binder | 汉高股份有限及两合公司 | 2021-10-26 | — | — | CN | claimed |
| CN-113543706-A | Electrode comprising a conductive acrylate-based pressure sensitive adhesive | 汉高股份有限及两合公司 | 2021-10-22 | — | — | CN | claimed |
| WO-2025053005-A1 | HERBICIDE COMPOSITION AND WEED CONTROL METHOD | 住友化学株式会社 | 2025-03-13 | — | — | WO | disclosed |
| CN-113543706-B | Electrode comprising a conductive acrylate-based pressure sensitive adhesive | 汉高股份有限及两合公司 | 2024-07-23 | — | — | CN | disclosed |
| CN-118235027-A | Ion conductive composition for thermal sensor | 汉高股份有限及两合公司 | 2024-06-21 | — | — | CN | disclosed |
| CN-117136192-A | Conjugated hepcidin mimetics | 领导医疗有限公司 | 2023-11-28 | — | — | CN | disclosed |
| CN-115210291-A | Method for producing polyether carbonate polyols | 科思创德国股份有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-115175738-A | Conjugates undergoing intramolecular rearrangement | 阿森迪斯药物股份有限公司 | 2022-10-11 | — | — | CN | disclosed |
| CN-114729115-A | Method for producing polyether carbonate polyols | 科思创知识产权两合公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114487198-A | Relative quantitative method of phosphorylated peptide | 江汉大学 | 2022-05-13 | — | — | CN | disclosed |
| CN-113557281-A | Dry electrode binder | 汉高股份有限及两合公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-113543706-A | Electrode comprising a conductive acrylate-based pressure sensitive adhesive | 汉高股份有限及两合公司 | 2021-10-22 | — | — | CN | disclosed |
| CN-113316604-A | Process for preparing diols | 科思创知识产权两合公司 | 2021-08-27 | — | — | CN | disclosed |
| CN-112654660-A | Method for separating out gas components | 科思创知识产权两合公司 | 2021-04-13 | — | — | CN | disclosed |