Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.43 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Sebacic Acid SCHEMBL5874411 | 0.98 | HPGD (0.47) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| Glutarate SCHEMBL5875052 | 0.97 | LTA4H (0.44) | HPGDHDAC3HDAC4HDAC1HDAC7 | |
| Hexanoate SCHEMBL5875213 | 0.94 | AKR1B1 (0.47) | HDAC11MAPTTDP1ALDH1A1FABP4 | |
| Succinic Acid SCHEMBL5874073 | 0.93 | NR4A2 (0.41) | KDM4EATMTDP1NPSR1ALDH1A1 | |
| Heptanoate SCHEMBL5875207 | 0.93 | GPR84 (0.49) | HPGDHDAC11MAPTTDP1ALDH1A1 | |
| Decanoic Acid SCHEMBL5874460 | 0.93 | GPR84 (0.49) | HPGDHDAC11MAPTTDP1ALDH1A1 | |
| Stearic Acid SCHEMBL5874660 | 0.93 | GPR84 (0.49) | HPGDHDAC11MAPTTDP1ALDH1A1 | |
| Nonanoate SCHEMBL5874695 | 0.93 | GPR84 (0.49) | HPGDHDAC11MAPTTDP1ALDH1A1 | |
| Octanoic Acid SCHEMBL5874717 | 0.93 | GPR84 (0.49) | HPGDHDAC11MAPTTDP1ALDH1A1 | |
| Valeric Acid SCHEMBL5874940 | 0.92 | CES2 (0.41) | HPGDHDAC3HDAC4HDAC1HDAC7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |