Known targets — ChEMBL curated mechanism
ADRB1CDK4CDK6CHRM2CHRM3DPP4DRD2DRD3DRD4EGFRHRH1HTR1BHTR1DHTR1FHTR2AHTR2CHTR4SLC6A2SLC6A4
The experimentally established mechanism targets of Succinic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 known ✓ | P08172 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.41 |
| ▸ | ITGAV | P06756 | 1/20 | 0.41 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.41 |
| ▸ | WNT3A | P56704 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | RBP4 | P02753 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | FPR1 | P21462 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5874263 | 0.93 | HPGD (0.45) | ITGB3ITGAVCTNNB1WNT3AALDH1A1 | |
| Glutarate SCHEMBL5875052 | 0.93 | LTA4H (0.44) | ITGB3ITGAVCTNNB1WNT3ACYP2C19 | |
| Butyric Acid SCHEMBL5874921 | 0.92 | FFAR3 (0.42) | ITGB3ITGAVCTNNB1WNT3ACYP2C19 | |
| Sebacic Acid SCHEMBL5874411 | 0.92 | HPGD (0.47) | ALDH1A1NPSR1KDM4EATMTDP1 | |
| Glycolic Acid SCHEMBL5179943 | 0.89 | CYP2C19 (0.39) | ITGB3ITGAVCTNNB1WNT3ACYP2C19 | |
| Propionic Acid SCHEMBL5874238 | 0.89 | HIF1A (0.39) | ITGB3ITGAVCTNNB1WNT3ACYP2C19 | |
| Malonic Acid SCHEMBL5874902 | 0.89 | GAA (0.41) | ITGB3ITGAVCTNNB1WNT3ACYP2C19 | |
| Valeric Acid SCHEMBL5874940 | 0.89 | CES2 (0.41) | ALDH1A1KDM4EATMTDP1FFAR1 | |
| Bicarbonate SCHEMBL5874331 | 0.89 | KMT2A (0.41) | CTNNB1WNT3ACYP2C19ALDH1A1NPSR1 | |
| Chloroacetic Acid SCHEMBL5874302 | 0.88 | HIF1A (0.38) | ITGB3ITGAVCTNNB1WNT3ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |