Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CHKA | P35790 | 1/20 | 0.35 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.34 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.34 |
| ▸ | CHRNB3 | Q05901 | 1/20 | 0.34 |
| ▸ | CHRNA6 | Q15825 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5874850 | 1.00 | CA2 (0.37) | CA2CA12CA1CA9CHKA | |
| SCHEMBL9596607 | 0.92 | HCAR2 (0.39) | CA2CA12CA1CA9CHKA | |
| SCHEMBL9596598 | 0.92 | HCAR2 (0.39) | CA2CA12CA1CA9CHKA | |
| SCHEMBL28719611 | 0.90 | HCAR2 (0.38) | CA2CA12CA1CA9CHKA | |
| Water SCHEMBL28189169 | 0.90 | HCAR2 (0.38) | CA2CA12CA1CA9CHKA | |
| SCHEMBL29040960 | 0.87 | CA12 (0.30) | CA2CA12CA1CA9 | |
| SCHEMBL29283212 | 0.86 | HCAR2 (0.47) | CA2CA12CA1CA9SIGMAR1 | |
| SCHEMBL27791412 | 0.84 | CA2 (0.35) | CA2CA12CA1CA9CHKA | |
| SCHEMBL27670396 | 0.83 | CA2 (0.34) | CA2CA12CA1CA9CHKA | |
| SCHEMBL27452767 | 0.82 | SIGMAR1 (0.41) | SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116507327-A | Chewable formulations | 礼蓝动物保健有限公司 | 2023-07-28 | — | — | CN | disclosed |
| CN-109115900-A | The method of LC-MS/MS method measurement (E) 3,4,5- trimethoxy cinnamoyl chloride | 中南粮油食品科学研究院有限公司 | 2019-01-01 | — | — | CN | disclosed |
| CN-108601724-A | gastric retention device | 克雷西奥生物科技有限公司 | 2018-09-28 | — | — | CN | disclosed |
| CN-108524445-A | Medical composition containing poorly water soluble drugs | 兴和株式会社 | 2018-09-14 | — | — | CN | disclosed |
| CN-103209660-B | Cannula for expandable medical device | W.L.戈尔及同仁股份有限公司 | 2016-11-02 | — | — | CN | disclosed |
| CN-104520280-B | Indene derivative, its preparation and the purposes as medicine | 埃斯特韦实验室有限公司 | 2016-09-07 | — | — | CN | disclosed |
| CN-104662021-B | Novel bicyclic pyridinones | 辉瑞大药厂 | 2016-08-24 | — | — | CN | disclosed |
| CN-102614179-B | As be used for the treatment of cognitive impairment, 1-[2-(2, the 4-dimethylphenylsulfanyl)-phenyl] piperazine of the compound to serotonin reabsorption, 5-HT3 and 5-HT1A activity with combination | H. LUNDHECK A/S (DK) | 2015-11-25 | — | — | CN | disclosed |
| CN-102617513-B | As be used for the treatment of cognitive impairment, 1-[2-(2, the 4-dimethylphenylsulfanyl)-phenyl] piperazine of the compound to serotonin reabsorption, 5-HT3 and 5-HT1A activity with combination | H. LUNDHECK A/S (DK) | 2015-09-23 | — | — | CN | disclosed |
| CN-104520280-A | Indene derivatives, their preparation and use as medicaments | ESTEVE LABOR DR | 2015-04-15 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| CN-1743302-A | Arylpiperazines having 5-hydroxyl-typtamine activity | LILLY CO ELI (US) | 2006-03-08 | — | — | CN | disclosed |
| CN-1712398-A | Diaryl amidine compound, its production, medicinal composition and use | DRUG INST CHINESE ACADEMY OF M (CN) | 2005-12-28 | — | — | CN | disclosed |
| CN-1227241-C | Having 5-hydroxytryptamine 1AReceptor-active arylpiperazines | LILLY CO ELI (US) | 2005-11-16 | — | — | CN | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| CN-1290258-A | Aryl piperazine compounds with 5-hydroxytryptamine 1A receptor activity | LILLY CO ELI (US) | 2001-04-04 | — | — | CN | disclosed |
| CN-1143318-A | Transdermal device containing polyvinylpyrrolidone as dissolution enhancer | NOVEN PHARMA (US) | 1997-02-19 | — | — | CN | disclosed |
| CN-1120838-A | Heterocyclic derivatives in the treatment of ischaemia and related diseases | SYNTEX PHARMA LTD (GB) | 1996-04-17 | — | — | CN | disclosed |
| EP-0089900-B1 | NEW N-((2-OXO-1-PYRROLIDINYL)ACETYL)PIPERAZINES, THE METHODS OF PRODUCING SUCH NEW COMPOUNDS AND THEIR SALTS AS WELL AS PHARMACEUTICAL PREPARATIONS FOR THERAPEUTIC USE CONTAINING THESE COMPOUNDS OR SALTS | PRODES S.A. (ES) | 1985-12-27 | — | — | EP | disclosed |
| EP-0089900-A1 | New N-((2-oxo-1-pyrrolidinyl)acetyl)piperazines, the methods of producing such new compounds and their salts as well as pharmaceutical preparations for therapeutic use containing these compounds or salts | PRODES S.A. (ES) | 1983-09-28 | — | — | EP | disclosed |