Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Diethanolamine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | RECQL | P46063 | 2/20 | 0.35 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | NSD2 | O96028 | 2/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.35 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diethanolamine SCHEMBL1022769 | 1.00 | CA5A (0.40) | CA5ACA5BTP53MEN1USP2 | |
| Diethanolamine SCHEMBL27699304 | 0.97 | CA5A (0.38) | CA5ACA5BTP53MEN1USP2 | |
| Diethanolamine SCHEMBL21596422 | 0.90 | CA2 (0.42) | TP53MEN1USP2KMT2ALMNA | |
| Diethanolamine SCHEMBL1829927 | 0.90 | CA2 (0.42) | TP53MEN1USP2KMT2ALMNA | |
| Diethanolamine SCHEMBL10933773 | 0.88 | CA2 (0.47) | CA5ACA5BTP53MEN1USP2 | |
| Sulfuric Acid SCHEMBL701165 | 0.87 | CA12 (0.50) | CA5ACA5BTP53MEN1KMT2A | |
| Sulfuric Acid SCHEMBL17673120 | 0.87 | CA12 (0.50) | CA5ACA5BTP53MEN1KMT2A | |
| Diethanolamine SCHEMBL11292760 | 0.85 | CA1 (0.37) | TP53MEN1USP2KMT2ALMNA | |
| Diethanolamine SCHEMBL8506349 | 0.83 | TP53 (0.32) | TP53MEN1USP2KMT2ALMNA | |
| Sulfuric Acid SCHEMBL8016897 | 0.83 | CYP2C19 (0.43) | CA5ACA5BTP53MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106163278-B | Alkanolamine sulfate water conditioners | 亨斯迈石油化学有限责任公司 | 2022-09-02 | — | — | CN | claimed |
| EP-3203839-B1 | ALKANOLAMINE SULFATE WATER CONDITIONERS | HUNTSMAN PETROCHEMICAL LLC (US) | 2019-09-04 | — | — | EP | claimed |
| EP-3203839-A1 | ALKANOLAMINE SULFATE WATER CONDITIONERS | Huntsman Petrochemical LLC (US) | 2017-08-16 | — | — | EP | claimed |
| US-20170202215-A1 | Alkanolamine Sulfate Water Conditioners | HUNTSMAN PETROCHEMICAL LLC (US) | 2017-07-20 | — | — | US | claimed |
| WO-2016057170-A1 | ALKANOLAMINE SULFATE WATER CONDITIONERS | HUNTSMAN PETROCHEMICAL LLC (US) | 2016-04-14 | — | — | WO | claimed |
| WO-2023238500-A1 | TREATMENT AGENT FOR CARBON FIBER PRECURSOR, AND CARBON FIBER PRECURSOR | 竹本油脂株式会社 | 2023-12-14 | — | — | WO | disclosed |
| CN-115023139-A | PPO formulations containing ether sulfates | 巴斯夫欧洲公司 | 2022-09-06 | — | — | CN | disclosed |
| CN-114980740-A | Novel additives for agrochemical formulations | 巴斯夫欧洲公司 | 2022-08-30 | — | — | CN | disclosed |
| CN-113498785-A | Growth regulator concentrates and uses thereof | 精细农用化学品有限公司 | 2021-10-15 | — | — | CN | disclosed |
| EP-2743262-B1 | Method for Obtaining a Triazine Compound with at least one Tertiary Amino Group | BOREALIS AGROLINZ MELAMINE (AT) | 2016-04-27 | — | — | EP | disclosed |
| EP-2743262-A1 | Method for Obtaining a Triazine Compound with at least one Tertiary Amino Group | Borealis Agrolinz Melamine GmbH (AT) | 2014-06-18 | — | — | EP | disclosed |
| US-8475584-B1 | Zinc clays, zinc organoclays, methods for making the same, and compositions containing the same | NIP RAYMOND LEE (TH) | 2013-07-02 | — | — | US | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5205960-A | Hydrolyzed alpha-olefin-maleic anhydride polymer acts as hydrotrope between phases; forms homogeneous single phase | S. C. JOHNSON & SON, INC. (US) | 1993-04-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170202215-A1 | Alkanolamine Sulfate Water Conditioners | SRM, SGMS1, SGMS2 | CA5A 3356/4885CA5B 4265/4885TP53 2009/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.