Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tetrapropylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 1/20 | 0.48 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrapropylammonium SCHEMBL5874101 | 0.94 | TSHR (0.42) | SLC22A1NFKB1CYP3A4TSHRNPSR1 | |
| Tetrabuthylammonium SCHEMBL5874496 | 0.86 | SLC22A1 (0.52) | SLC22A1NFKB1CYP3A4TSHRCA1 | |
| Tetrapropylammonium SCHEMBL5574321 | 0.86 | SLC22A1 (0.48) | SLC22A1NFKB1CYP3A4TSHRNPSR1 | |
| Cadaverine Tartrate SCHEMBL15561037 | 0.85 | SLC22A1 (0.45) | SLC22A1CYP3A4TSHRCA2GPR84 | |
| Tetrapropylammonium SCHEMBL108600 | 0.85 | SLC22A1 (0.59) | SLC22A1FFAR3HDAC3HDAC1HDAC2 | |
| Tetrapropylammonium SCHEMBL5874099 | 0.83 | TSHR (0.50) | SLC22A1TSHRGPR84FFAR1HDAC1 | |
| Tetrapropylammonium SCHEMBL5575007 | 0.83 | SLC22A1 (0.50) | SLC22A1NFKB1CYP3A4TSHRNPSR1 | |
| Cadaverine Tartrate SCHEMBL9094501 | 0.83 | SLC22A1 (0.52) | SLC22A1CYP3A4TSHRCA2GPR84 | |
| Tetrapropylammonium SCHEMBL108342 | 0.82 | SLC22A1 (0.62) | SLC22A1FFAR3HDAC3HDAC1HDAC2 | |
| Tetrapropylammonium SCHEMBL5874618 | 0.81 | CA4 (0.45) | SLC22A1NFKB1CYP3A4TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |