Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A1 | O15245 | 3/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL5874496 | 0.94 | SLC22A1 (0.52) | SLC22A1TSHRCYP3A4GPR84CA1 | |
| Tetrabuthylammonium SCHEMBL5874524 | 0.92 | SLC22A1 (0.55) | SLC22A1TSHRCYP3A4GPR84FFAR1 | |
| Cadaverine Tartrate SCHEMBL15561037 | 0.91 | SLC22A1 (0.45) | SLC22A1TSHRCYP3A4TDP1LMNA | |
| Cadaverine Tartrate SCHEMBL9094501 | 0.90 | SLC22A1 (0.52) | SLC22A1TSHRCYP3A4GPR84FFAR1 | |
| Tetrabuthylammonium SCHEMBL11220045 | 0.90 | SLC22A1 (0.52) | SLC22A1TSHRCYP3A4GPR84FFAR1 | |
| Tetrapropylammonium SCHEMBL5874101 | 0.88 | TSHR (0.42) | SLC22A1TSHRCYP3A4TDP1LMNA | |
| Cadaverine Tartrate SCHEMBL8435543 | 0.84 | DNM1 (0.52) | TSHRCYP3A4TDP1LMNABLM | |
| Cetrimonium SCHEMBL5533047 | 0.84 | DNM1 (0.52) | TSHRCYP3A4TDP1LMNABLM | |
| Cadaverine Tartrate SCHEMBL8437270 | 0.84 | DNM1 (0.52) | TSHRCYP3A4TDP1LMNABLM | |
| Cadaverine Tartrate SCHEMBL15561036 | 0.82 | SLC22A1 (0.52) | SLC22A1TSHRCYP3A4GPR84FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119372312-A | Biomarker, reagent and kit for early recognition of metastatic lung cancer and application of biomarker | 四川省肿瘤医院 | 2025-01-28 | — | — | CN | claimed |
| CN-112129938-B | Use of UDP-Glc in lung cancer metastasis assessment | 中国科学院分子细胞科学卓越创新中心 | 2023-08-18 | — | — | CN | claimed |
| CN-112129938-A | Application of UDP-Glc in lung cancer metastasis assessment | 中国科学院分子细胞科学卓越创新中心 | 2020-12-25 | — | — | CN | claimed |
| US-20160141725-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | claimed |
| CN-119684381-A | Crystalline forms of nicotinamide riboside furanoside salts and nutritional supplements and pharmaceutical compositions containing same | 生物合成股份公司 | 2025-03-25 | — | — | CN | disclosed |
| CN-119462782-A | Method for producing nicotinamide riboside salts, nicotinamide riboside salts per se and use thereof | 生物合成股份公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119372312-A | Biomarker, reagent and kit for early recognition of metastatic lung cancer and application of biomarker | 四川省肿瘤医院 | 2025-01-28 | — | — | CN | disclosed |
| CN-117751182-A | Method for amplifying human granulocyte-macrophage progenitor cells and application thereof | 南加利福尼亚大学 | 2024-03-22 | — | — | CN | disclosed |
| CN-112129938-B | Use of UDP-Glc in lung cancer metastasis assessment | 中国科学院分子细胞科学卓越创新中心 | 2023-08-18 | — | — | CN | disclosed |
| US-11485915-B2 | Methods of using ionic liquids as corrosion inhibitors | BAKER HUGHES HOLDINGS LLC (US) | 2022-11-01 | — | — | US | disclosed |
| CN-112121167-B | Application of UDP-Glc in preparing medicine for inhibiting lung cancer metastasis | 中国科学院分子细胞科学卓越创新中心 | 2022-10-11 | — | — | CN | disclosed |
| CN-107710462-B | Electrochemical hydrogen storage electrode and battery | 巴斯夫公司 | 2022-08-02 | — | — | CN | disclosed |
| US-20160329560-A1 | Electrochemical Hydrogen Storage Electrodes and Cells | BASF CORPORATION (US) | 2016-11-10 | — | — | US | disclosed |
| US-20160141725-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-20160141724-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-20160141726-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-20160141727-A1 | Electrolytes and Metal Hydride Batteries | BASF CORPORATION | 2016-05-19 | — | — | US | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5933693-A | Electroconductive elastic member and electrophotographic apparatus using same | BRIDGESTONE CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |