Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Piperidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CA5A | P35218 | 1/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.47 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CHKA | P35790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL4890817 | 0.97 | — | — | |
| Nitric Acid SCHEMBL6680089 | 0.87 | — | — | |
| Nitric Acid SCHEMBL11794277 | 0.84 | CA5A (0.57) | CA5ACA5BCXCR4SMN1; SMN2 | |
| Piperazine SCHEMBL5875381 | 0.84 | CA5A (0.57) | CA5ACA5BCXCR4SMN1; SMN2 | |
| Piperazine SCHEMBL14695887 | 0.84 | CA5A (0.57) | CA5ACA5BCXCR4SMN1; SMN2 | |
| Cyclohexane SCHEMBL28192319 | 0.80 | CA5A (0.73) | ALDH1A1CA5ACA5B | |
| Cyclohexane SCHEMBL2019979 | 0.80 | CA5A (0.73) | ALDH1A1CA5ACA5B | |
| Cyclohexane SCHEMBL8006197 | 0.80 | CA5A (0.73) | ALDH1A1CA5ACA5B | |
| Piperidine SCHEMBL23753734 | 0.75 | ALDH1A1 (0.60) | ALDH1A1CXCR4SMN1; SMN2 | |
| Pyrrolidine SCHEMBL3238959 | 0.73 | ALDH1A1 (0.67) | ALDH1A1CXCR4SMN1; SMN2CA2CHKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-58141480-A | — | — | None | — | — | JP | disclosed |
| CN-215086994-U | Piperidine production autoclave convenient to add nickel catalyst | 湖北江盐天祥化工有限公司 | 2021-12-10 | — | — | CN | disclosed |
| CN-214514230-U | Piperidine derivative preparation is with constant temperature heating magnetic stirrers | 四川安派博生物科技有限公司 | 2021-10-29 | — | — | CN | disclosed |
| CN-213995870-U | Reation kettle is used in production of silicon hetero-piperidine | 含山捷化生物科技有限公司 | 2021-08-20 | — | — | CN | disclosed |
| CN-105709855-B | A kind of preparation method of palladium hydrogenation catalyst, the catalyst prepared by this method and the method for using the catalyst preparation piperidines | 北京旭阳科技有限公司 | 2018-06-19 | — | — | CN | disclosed |
| CN-108148018-A | The preparation method of thiofide DPTT-6 | 蔚林新材料科技股份有限公司 | 2018-06-12 | — | — | CN | disclosed |
| EP-2927204-B1 | LIQUID PROPELLANT | CARLIT HOLDINGS CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |
| CN-206544989-U | A kind of purifying plant of hexahydropyridine | 上海凌凯医药科技有限公司 | 2017-10-10 | — | — | CN | disclosed |
| CN-105709855-A | Preparation method of palladium hydrogenation catalyst, catalyst prepared through the method and method for preparing piperidine through catalyst | 北京旭阳科技有限公司 | 2016-06-29 | — | — | CN | disclosed |
| CN-100546961-C | The preparation method of perillalcohol | UNIV SOUTH CHINA TECH (CN) | 2009-10-07 | — | — | CN | disclosed |
| CN-101010130-A | Ionic polymer membranes | BP CORP NORTH AMERICA INC (US) | 2007-08-01 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| CN-1680236-A | Preparation of perilla alcohol | HUANAN SCIENCE & ENGINEERING (CN) | 2005-10-12 | — | — | CN | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-4945184-A | REACTING KETONE AND PARAFORMALDEHYDE USING SECONDARY AMINE AND CARBOXYLIC ACID CATALYST MIXTURE | ARISTECH CHEMICAL CORPORATION (US) | 1990-07-31 | — | — | US | disclosed |
| US-4814305-A | PHOSPHORUS, MOLYBDENUM, ALKALI METAL | MITSUBISHI RAYON CO., LTD. (JP) | 1989-03-21 | — | — | US | disclosed |
| JP-S58141480-A | SLIP PAPER FOR CASSETTE TAPE | DAINIPPON PRINTING CO LTD | 1983-08-22 | — | — | JP | disclosed |