Glutarate

Glutarate

SCHEMBL5874599

CCN.CCN.O=C(O)CCCC(=O)O

nearest known ligand 0.69

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.69
HDAC11 Q96DB2 6/20 0.63
TSHR P16473 5/20 0.63
LMNA P02545 3/20 0.63
KMT2A Q03164 3/20 0.63
THRB P10828 2/20 0.63
BLM P54132 2/20 0.63
NPSR1 Q6W5P4 2/20 0.63
GABRR3 A8MPY1 1/20 0.63
GABRP O00591 1/20 0.63
GABRD O14764 1/20 0.63
HDAC3 O15379 1/20 0.63
GABBR2 O75899 1/20 0.63
CYP1A2 P05177 1/20 0.63
GABRA1 P14867 1/20 0.63
GABRB1 P18505 1/20 0.63
GABRG2 P18507 1/20 0.63
GABRR1 P24046 1/20 0.63
GABRB3 P28472 1/20 0.63
GABRR2 P28476 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Glutarate SCHEMBL5874605 1.00 SLC22A6 (0.69) SLC22A6HDAC11TSHRLMNAKMT2A
Adipic Acid SCHEMBL5874787 0.94 LMNA (0.69) SLC22A6HDAC11TSHRLMNAKMT2A
Adipic Acid SCHEMBL5874779 0.94 LMNA (0.69) SLC22A6HDAC11TSHRLMNAKMT2A
Azelaic Acid SCHEMBL29048653 0.91 TSHR (0.71) SLC22A6HDAC11TSHRLMNAKMT2A
Sebacic Acid SCHEMBL5875156 0.91 TSHR (0.71) SLC22A6HDAC11TSHRLMNAKMT2A
Sebacic Acid SCHEMBL5875166 0.91 TSHR (0.71) SLC22A6HDAC11TSHRLMNAKMT2A
Glutarate SCHEMBL722744 0.88 HDAC11 (0.65) SLC22A6HDAC11TSHRLMNAKMT2A
Valeric Acid SCHEMBL5874826 0.88 AKR1B1 (0.70) SLC22A6HDAC11TSHRLMNAKMT2A
Glutarate SCHEMBL16783937 0.87 SLC22A6 (0.79) SLC22A6HDAC11TSHRLMNAKMT2A
Glutarate SCHEMBL5874920 0.87 SLC22A6 (0.79) SLC22A6HDAC11TSHRLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed