Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.65 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 3/20 | 0.69 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.68 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.68 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.68 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.65 |
| ▸ | PPARG | P37231 | 7/20 | 0.65 |
| ▸ | PPARD | Q03181 | 7/20 | 0.65 |
| ▸ | PPARA | Q07869 | 7/20 | 0.65 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.65 |
| ▸ | TSHR | P16473 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.65 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.65 |
| ▸ | TLR2 | O60603 | 2/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | FABP4 | P15090 | 2/20 | 0.65 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL5874787 | 1.00 | LMNA (0.69) | LMNANFKB1AKR1B1CYP2D6GPR84 | |
| Azelaic Acid SCHEMBL29048653 | 0.97 | TSHR (0.71) | LMNANFKB1AKR1B1CYP2D6GPR84 | |
| Sebacic Acid SCHEMBL5875166 | 0.97 | TSHR (0.71) | LMNANFKB1AKR1B1CYP2D6GPR84 | |
| Sebacic Acid SCHEMBL5875156 | 0.97 | TSHR (0.71) | LMNANFKB1AKR1B1CYP2D6GPR84 | |
| Glutarate SCHEMBL5874599 | 0.94 | SLC22A6 (0.69) | LMNANFKB1AKR1B1CYP2D6GPR84 | |
| Glutarate SCHEMBL5874605 | 0.94 | SLC22A6 (0.69) | LMNANFKB1AKR1B1CYP2D6GPR84 | |
| Adipic Acid SCHEMBL11870859 | 0.92 | NFKB1 (0.59) | LMNANFKB1AKR1B1CYP2D6GPR84 | |
| Hexanoate SCHEMBL27850335 | 0.92 | AKR1B1 (0.84) | LMNAAKR1B1GPR84PPARGPPARD | |
| Hexanoate SCHEMBL5875188 | 0.92 | AKR1B1 (0.84) | LMNAAKR1B1GPR84PPARGPPARD | |
| Heptanoate SCHEMBL5874770 | 0.89 | GPR84 (0.85) | LMNAAKR1B1GPR84PPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102702940-A | Floating coating for automobile | TIANCHANG JULONG TRAVEL PAINT CO LTD | 2012-10-03 | — | — | CN | claimed |
| CN-119330823-A | Long carbon chain hydroxyl-containing branched dicarboxylic acid, and preparation method and application thereof | 华中师范大学 | 2025-01-21 | — | — | CN | disclosed |
| CN-101535403-B | Thermoplastic elastomer blend compositions | DU PONT | 2012-01-04 | — | — | CN | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| EP-0227433-A2 | Electrolyte solution of quaternary ammonium salt for electrolytic capacitor | MITSUBISHI PETROCHEMICAL CO., LTD. (JP) | 1987-07-01 | — | — | EP | disclosed |