Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SCSF1RDRD2FLT1FLT3FLT4HTR1BHTR1DHTR1FKDRKITMETOPRD1OPRK1OPRM1PDGFRAPDGFRBRET
The experimentally established mechanism targets of Tetrabuthylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.46 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Malic Acid SCHEMBL11775910 | 0.90 | DNM1 (0.50) | GPR84SLC22A1FFAR1SMN1; SMN2 | |
| Tetrapropylammonium SCHEMBL5874618 | 0.89 | CA4 (0.45) | GPR84SLC22A1CA4CA1FFAR1 | |
| Tetrabuthylammonium SCHEMBL5874718 | 0.87 | CA4 (0.59) | SLC22A1CA4CA1 | |
| Tetrabuthylammonium SCHEMBL9094612 | 0.86 | CA4 (0.57) | SLC22A1CA4CA1 | |
| Tetrabuthylammonium SCHEMBL5874725 | 0.85 | SMN1; SMN2 (0.58) | GPR84SLC22A1FFAR1SMN1; SMN2 | |
| Malic Acid SCHEMBL8437740 | 0.85 | DNM1 (0.48) | GPR84 | |
| Cetrimonium SCHEMBL8437300 | 0.85 | DNM1 (0.48) | GPR84 | |
| Malic Acid SCHEMBL8437259 | 0.85 | DNM1 (0.48) | GPR84 | |
| Tetrabuthylammonium SCHEMBL31344126 | 0.83 | SLC22A1 (0.48) | SLC22A1CA1CA2 | |
| Tetrabuthylammonium SCHEMBL5874496 | 0.83 | SLC22A1 (0.52) | GPR84SLC22A1CA1FFAR1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| US-5933693-A | Electroconductive elastic member and electrophotographic apparatus using same | BRIDGESTONE CORPORATION (JP) | 1999-08-03 | — | — | US | disclosed |