Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SCSF1RDRD2FLT1FLT3FLT4HTR1BHTR1DHTR1FKDRKITMETOPRD1OPRK1OPRM1PDGFRAPDGFRBRET
The experimentally established mechanism targets of Tetrylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.70 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 1/20 | 0.37 |
| ▸ | CPT2 | P23786 | 1/20 | 0.36 |
| ▸ | CPT1A | P50416 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | KCNA1 | Q09470 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | HRH1 | P35367 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrylammonium SCHEMBL5874843 | 0.85 | CA4 (0.48) | CA4SLC22A16TSHRNFKB1KCNA1 | |
| Malic Acid SCHEMBL4142948 | 0.84 | CA4 (0.80) | CA4SLC22A16CA2CTSLCPT2 | |
| Tetrapropylammonium SCHEMBL5874611 | 0.83 | CA4 (0.64) | CA4SLC22A16CA2CTSLCPT2 | |
| Malic Acid SCHEMBL11775901 | 0.82 | DNM1 (0.52) | CA4CPT2CPT1ATSHRCYP3A4 | |
| Malic Acid SCHEMBL1311966 | 0.82 | CA4 (0.76) | CA4SLC22A16CA2CTSLCPT2 | |
| Malic Acid SCHEMBL27944022 | 0.82 | CA4 (0.81) | CA4SLC22A16CA2CTSLTSHR | |
| Malic Acid SCHEMBL118155 | 0.81 | CA4 (0.94) | CA4SLC22A16CA2CTSLCPT2 | |
| Malic Acid SCHEMBL21815132 | 0.81 | CA4 (1.00) | CA4SLC22A16CA2CTSLCPT2 | |
| Malic Acid SCHEMBL1093517 | 0.81 | CA4 (0.94) | CA4SLC22A16CA2CTSLCPT2 | |
| Malic Acid SCHEMBL20994738 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |