Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SCSF1RDRD2FLT1FLT3FLT4HTR1BHTR1DHTR1FKDRKITMETOPRD1OPRK1OPRM1PDGFRAPDGFRBRET
The experimentally established mechanism targets of Tetrapropylammonium. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 2/20 | 0.64 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CPT2 | P23786 | 1/20 | 0.34 |
| ▸ | CPT1A | P50416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetrabuthylammonium SCHEMBL5874718 | 0.89 | CA4 (0.59) | CA4SLC22A1NFKB1CA1CPT2 | |
| Tetrabuthylammonium SCHEMBL9094612 | 0.87 | CA4 (0.57) | CA4SLC22A1NFKB1CA1CPT2 | |
| Tetrapropylammonium SCHEMBL5874618 | 0.86 | CA4 (0.45) | CA4SLC22A1NFKB1CYP3A4TSHR | |
| Tetrylammonium SCHEMBL5874833 | 0.83 | CA4 (0.70) | CA4SLC22A16CA2NFKB1CYP3A4 | |
| Malic Acid SCHEMBL11775901 | 0.83 | DNM1 (0.52) | CA4SLC22A1CYP3A4TSHRCPT2 | |
| Malic Acid SCHEMBL4142948 | 0.81 | CA4 (0.80) | CA4SLC22A16CA2CTSLCPT2 | |
| Malic Acid SCHEMBL8437254 | 0.80 | CA4 (0.53) | CA4NFKB1CYP3A4TSHRCPT2 | |
| Cetrimonium SCHEMBL8437296 | 0.80 | CA4 (0.53) | CA4NFKB1CYP3A4TSHRCPT2 | |
| Malic Acid SCHEMBL8437735 | 0.80 | CA4 (0.53) | CA4NFKB1CYP3A4TSHRCPT2 | |
| Tetrapropylammonium SCHEMBL105101 | 0.80 | CA1 (0.48) | CA4SLC22A16SLC22A1CA2NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
| WO-1998030318-A2 | COMPOUNDS FOR PRODUCING NANOPOROUS POLYMERS, NANOCOMPOSITE AND MEMBRANES THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1998-07-16 | — | — | WO | disclosed |