Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NAAA | Q02083 | 2/20 | 0.51 |
| ▸ | DGKA | P23743 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PAM | P19021 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 3/20 | 0.42 |
| ▸ | CES1 | P23141 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5875291 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL8433164 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL8704444 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL8706673 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL8682250 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL8707838 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL8707302 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL5874578 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL5874212 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA | |
| SCHEMBL5874155 | 1.00 | L3MBTL1 (0.53) | L3MBTL1MEN1KMT2ATDP1NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2999711-B1 | POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS | SPERO THERAPEUTICS INC (US) | 2022-06-29 | — | — | EP | disclosed |
| CN-105308065-B | Polymyxin derivatives and their use in combination therapy with different antibiotics | 斯佩罗治疗公司 | 2021-10-15 | — | — | CN | disclosed |
| US-20200179254-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | HENKEL AG & CO. KGAA (DE) | 2020-06-11 | — | — | US | disclosed |
| US-10407467-B2 | Polymyxin derivatives and their use in combination therapy together with different antibiotics | NEW PHARMA LICENCE HOLDINGS LIMITED (MT) | 2019-09-10 | — | — | US | disclosed |
| US-20190240129-A1 | CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | HENKEL AG & CO. KGAA (DE) | 2019-08-08 | — | — | US | disclosed |
| EP-3518878-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | Henkel AG & Co. KGaA (DE) | 2019-08-07 | — | — | EP | disclosed |
| US-20190216703-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | HENKEL AG & CO. KGAA (DE) | 2019-07-18 | — | — | US | disclosed |
| US-20190216714-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | HENKEL AG & CO. KGAA (DE) | 2019-07-18 | — | — | US | disclosed |
| US-20160222061-A1 | Polymyxin Derivatives and Their Use in Combination Therapy Together with Different Antibiotics | NEW PHARMA LICENCE HOLDINGS LIMITED (MT) | 2016-08-04 | — | — | US | disclosed |
| EP-2999711-A1 | POLYMYXIN DERIVATIVES AND THEIR USE IN COMBINATION THERAPY TOGETHER WITH DIFFERENT ANTIBIOTICS | New Pharma Licence Holdings Limited (MT) | 2016-03-30 | — | — | EP | disclosed |
| US-7128976-B2 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2006-10-31 | — | — | US | disclosed |
| US-20030091838-A1 | Composition for film formation, method of film formation, and silica-based film | JSR CORPORATION (JP) | 2003-05-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190240129-A1 | CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | KRT18, CUTA, S100A10 | L3MBTL1 4779/4885MEN1 3369/4885KMT2A 242/4885 |
| US-20160222061-A1 | Polymyxin Derivatives and Their Use in Combination Therapy Together with Different Antibiotics | MRPS18A, MRPL21, RRP1B | L3MBTL1 1525/4885MEN1 991/4885KMT2A 3734/4885 |
| US-20190216703-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | KRT18, SRRM2, IK | L3MBTL1 4634/4885MEN1 4505/4885KMT2A 912/4885 |
| US-10407467-B2 | Polymyxin derivatives and their use in combination therapy together with different antibiotics | MRPS18A, MRPL21, RRP1B | L3MBTL1 1525/4885MEN1 991/4885KMT2A 3734/4885 |
| US-20190216714-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | KRT18, CD44, PCNA | L3MBTL1 4760/4885MEN1 2001/4885KMT2A 97/4885 |
| US-20200179254-A1 | IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION | KRT18, CUTA, DSG1 | L3MBTL1 4594/4885MEN1 3038/4885KMT2A 59/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.