Cadaverine Tartrate

Cadaverine Tartrate

SCHEMBL5875448

CN(C)C.O=C(O)C(O)C(O)C(=O)O

nearest known ligand 0.71

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CHRM1CHRM2CHRM3CHRM4ESR1ESR2GABRA1GABRB1GABRG2GBA1HRH1HTR1DHTR2AOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.71
TP53 P04637 1/20 0.47
NFKB1 P19838 1/20 0.41
CYP2C19 P33261 1/20 0.41
CYP2C9 P11712 1/20 0.38
PDE4A P27815 1/20 0.38
LMNA P02545 2/20 0.33
OR51E2 Q9H255 1/20 0.33
CYP3A4 P08684 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
BLM P54132 1/20 0.33
PMP22 Q01453 1/20 0.33
ALDH1A1 P00352 1/20 0.33
THRB P10828 1/20 0.33
RECQL P46063 1/20 0.33
PGD P52209 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Cadaverine Tartrate SCHEMBL5875445 1.00 TSHR (0.71) TSHRTP53NFKB1CYP2C19CYP2C9
Cadaverine Tartrate SCHEMBL2216947 0.89 TSHR (0.91) TSHRTP53NFKB1CYP2C19CYP2C9
Cadaverine Tartrate SCHEMBL8945831 0.85 TSHR (0.83) TSHRTP53NFKB1CYP2C19CYP2C9
Cadaverine Tartrate SCHEMBL4778934 0.85 TSHR (0.83) TSHRTP53NFKB1CYP2C19CYP2C9
Tartaric Acid SCHEMBL5762 0.84 TSHR (1.00) TSHRTP53NFKB1CYP2C19CYP2C9
Cadaverine Tartrate SCHEMBL1062721 0.84 TSHR (1.00) TSHRTP53NFKB1CYP2C19CYP2C9
Cadaverine Tartrate SCHEMBL848 0.84 TSHR (1.00) TSHRTP53NFKB1CYP2C19CYP2C9
Cadaverine Tartrate SCHEMBL116846 0.84 TSHR (1.00) TSHRTP53NFKB1CYP2C19CYP2C9
Cadaverine Tartrate SCHEMBL1431070 0.84 TSHR (1.00) TSHRTP53NFKB1CYP2C19CYP2C9
Cadaverine Tartrate SCHEMBL31427568 0.84 TSHR (1.00) TSHRTP53NFKB1CYP2C19CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109438268-B Choline bitartrate and preparation method thereof 济南蓬勃生物技术有限公司 2021-08-03 CN claimed
CN-119462685-A Arteannuin derivative and application thereof in treating cerebral apoplexy 上海英诺富成生物科技有限公司 2025-02-18 CN disclosed
CN-109438268-B Choline bitartrate and preparation method thereof 济南蓬勃生物技术有限公司 2021-08-03 CN disclosed
CN-109438268-B Choline bitartrate and preparation method thereof 济南蓬勃生物技术有限公司 2021-08-03 CN disclosed
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2020-06-11 US disclosed
WO-2020078408-A1 CHOLINE BITARTRATE AND PREPARATION METHOD THEREFOR 济南蓬勃生物技术有限公司 2020-04-23 WO disclosed
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-08-08 US disclosed
EP-3518878-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION Henkel AG & Co. KGaA (DE) 2019-08-07 EP disclosed
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION HENKEL AG & CO. KGAA (DE) 2019-07-18 US disclosed
US-7128976-B2 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2006-10-31 US disclosed
US-20030091838-A1 Composition for film formation, method of film formation, and silica-based film JSR CORPORATION (JP) 2003-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190240129-A1 CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, S100A10 TSHR 3146/4885TP53 2105/4885NFKB1 3643/4885
US-20190216703-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, SRRM2, IK TSHR 1850/4885TP53 2548/4885NFKB1 3996/4885
US-20190216714-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CD44, PCNA TSHR 3345/4885TP53 1209/4885NFKB1 2864/4885
US-20200179254-A1 IMPROVED CONDITIONING HAIR TREATMENT PRODUCT WITH WASHOUT PROTECTION KRT18, CUTA, DSG1 TSHR 2235/4885TP53 1442/4885NFKB1 2831/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.