Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIN1 | Q13526 | 6/20 | 0.59 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5280678 | 1.00 | PIN1 (0.59) | PIN1CHRM1KDM4ERAB9AGAA | |
| SCHEMBL30042883 | 1.00 | PIN1 (0.59) | PIN1CHRM1KDM4ERAB9AGAA | |
| SCHEMBL7267155 | 1.00 | PIN1 (0.59) | PIN1CHRM1KDM4ERAB9AGAA | |
| SCHEMBL7211356 | 0.85 | CHRM1 (0.62) | PIN1CHRM1KDM4ERAB9AGAA | |
| SCHEMBL5325374 | 0.85 | CHRM1 (0.62) | PIN1CHRM1KDM4ERAB9AGAA | |
| SCHEMBL11100952 | 0.84 | KDM4E (0.59) | PIN1KDM4ERAB9ACYP1A2ALDH1A1 | |
| SCHEMBL6530115 | 0.83 | MAPT (0.59) | PIN1CHRM1KDM4ERAB9AALDH1A1 | |
| SCHEMBL38661628 | 0.82 | PIN1 (0.62) | PIN1CHRM1KDM4ERAB9AGAA | |
| SCHEMBL15156683 | 0.82 | PIN1 (0.62) | PIN1CHRM1KDM4ERAB9AGAA | |
| SCHEMBL17771956 | 0.81 | KDM4E (0.51) | PIN1KDM4EGAACYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2382206-B1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES | AQUILUS PHARMACEUTICALS INC (US) | 2016-03-23 | — | — | EP | disclosed |
| US-8765953-B2 | Compounds and methods for the treatment of pain and other diseases | AQUILUS PHARMACEUTICALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-8765953-B2 | Compounds and methods for the treatment of pain and other diseases | AQUILUS PHARMACEUTICALS, INC. (US) | 2014-07-01 | — | — | US | disclosed |
| US-20110257222-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES | AQUILUS PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| US-20110257222-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES | AQUILUS PHARMACEUTICALS, INC. (US) | 2011-10-20 | — | — | US | disclosed |
| US-20060155107-A1 | SSTR1-selective analogs | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2006-07-13 | — | — | US | disclosed |
| US-7019109-B2 | Cyclic somatostatin for use in the treatment and prevention of tumor propagation | THE SALK INSTITUTE FOR BILOGICAL STUDIES (US) | 2006-03-28 | — | — | US | disclosed |
| US-20020173618-A1 | SSTR1-selective analogs | SALK INSTITUTE OF BIOLOGICAL STUDIES, THE | 2002-11-21 | — | — | US | disclosed |
| EP-0871666-A1 | RECEPTOR-SELECTIVE SOMATOSTATIN ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-10-21 | — | — | EP | disclosed |
| US-5750499-A | ANTITUMOR | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1998-05-12 | — | — | US | disclosed |
| WO-1997014715-A1 | RECEPTOR-SELECTIVE SOMATOSTATIN ANALOGS | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1997-04-24 | — | — | WO | disclosed |
| US-4740500-A | OLIGOPEPTIDES, PROTECTED, ON RESIN SUPPORT | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 1988-04-26 | — | — | US | disclosed |
| EP-0042753-B1 | NONAPEPTIDE AND DECAPEPTIDE AGONISTS OF LUTEINIZING HORMONE RELEASING HORMONE CONTAINING HETEROCYCLIC AMINO ACID RESIDUES, METHODS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOUNDS CONTAINING THEM, AND THEIR PHARMACEUTICAL USE | SYNTEX (U.S.A.) INC. (US) | 1984-03-21 | — | — | EP | disclosed |
| US-4318905-A | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues | SYNTEX (U.S.A.) INC. (US) | 1982-03-09 | — | — | US | disclosed |
| EP-0042753-A1 | Nonapeptide and decapeptide agonists of luteinizing hormone releasing hormone containing heterocyclic amino acid residues, methods for their preparation, pharmaceutical compounds containing them, and their pharmaceutical use | SYNTEX (U.S.A.) INC. (US) | 1981-12-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110257222-A1 | COMPOUNDS AND METHODS FOR THE TREATMENT OF PAIN AND OTHER DISEASES | MMP3, MMP9, MMP10 | PIN1 225/4885CHRM1 4058/4885KDM4E 1170/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.