Lysine

Lysine

SCHEMBL587923

NCCCC[C@H](N)C(=O)[O-].NCCCC[C@H](N)C(=O)[O-].[Mg+2]

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

PPARDPTGS1PTGS2dacAdacBdacCftsImrcAmrcBmrdA

The experimentally established mechanism targets of Lysine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
GSR P00390 1/20 0.61
RNPEP Q9H4A4 1/20 0.43
GNAI3 P08754 1/20 0.43
GNAO1 P09471 1/20 0.43
GNAI1 P63096 1/20 0.43
DPP7 Q9UHL4 9/20 0.42
DPP8 Q6V1X1 5/20 0.42
DPP9 Q86TI2 5/20 0.42
DPP4 P27487 3/20 0.42
CPB2 Q96IY4 2/20 0.39
FAP Q12884 1/20 0.38
MMP2 P08253 1/20 0.37
ARG1 P05089 1/20 0.36
ARG2 P78540 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lysine SCHEMBL587922 1.00 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL17352177 0.98 GSR (0.59) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL17352176 0.98 GSR (0.59) GSRRNPEPGNAI3GNAO1GNAI1
SCHEMBL31241164 0.98 GSR (0.59) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL25283016 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL1281705 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL5691753 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL3427044 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL7197544 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1
Lysine SCHEMBL1034337 0.95 GSR (0.61) GSRRNPEPGNAI3GNAO1GNAI1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 237 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12564644-B2 Cyclodextrin complexes of specialized proresolving mediators THETIS PHARMACEUTICALS LLC (US) 2026-03-03 US claimed
CN-119949497-A Formula powder containing multiple amino acids and preparation method thereof 山东美吉客生物科技有限公司 2025-05-09 CN claimed
EP-4532464-A1 AGRICULTURALLY USEFUL MINERAL AMINO ACID COMPLEXES Statera Ag, LLC (US) 2025-04-09 EP claimed
EP-4486393-A2 CYCLODEXTRIN COMPLEXES OF SPECIALIZED PRORESOLVING MEDIATORS Thetis Pharmaceuticals LLC (US) 2025-01-08 EP claimed
US-20240408229-A1 CYCLODEXTRIN COMPLEXES OF SPECIALIZED PRORESOLVING MEDIATORS THETIS PHARMACEUTICALS LLC (US) 2024-12-12 US claimed
EP-4351609-A1 ORAL COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF DISORDERS ASSOCIATED WITH MENOPAUSE Pizeta Pharma S.P.A. (IT) 2024-04-17 EP claimed
WO-2023230428-A1 AGRICULTURALLY USEFUL MINERAL AMINO ACID COMPLEXES STATERA AG, LLC (US) 2023-11-30 WO claimed
WO-2023168245-A2 CYCLODEXTRIN COMPLEXES OF SPECIALIZED PRORESOLVING MEDIATORS THETIS PHARMACEUTICALS LLC (US) 2023-09-07 WO claimed
WO-2022259195-A1 ORAL COMPOSITION FOR THE TREATMENT AND/OR PREVENTION OF DISORDERS ASSOCIATED WITH MENOPAUSE. PIZETA PHARMA S.p.A. (IT) 2022-12-15 WO claimed
CN-112675160-A Amino acid mineral salt trace element composition and preparation method thereof 河北力维素科技有限公司 2021-04-20 CN claimed
CN-102783691-A Calcium-magnesium hydrogen producing agent ZHILIN LI 2012-11-21 CN claimed
EP-2416786-A1 PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF Cypress Pharmaceutical, Inc. (US) 2012-02-15 EP claimed
US-20110045063-A2 PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF CYPRESS PHARMACEUTICAL, INC. (US) 2011-02-24 US claimed
CN-101913237-A Manufacturing method of high-temperature resistant and corrosion-resistant polyphenyl thioether composite tube XUN CHEN 2010-12-15 CN claimed
US-7815943-B2 Cardiovascular therapy composition including transfer factor and therapeutic methods including use of the composition 4LIFE RESEARCH, LC (US) 2010-10-19 US claimed
WO-2010117370-A1 PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF CYPRESS PHARMACEUTICALS, INC. (US) 2010-10-14 WO claimed
US-20090269399-A1 PHOSPHATE-BINDING MAGNESIUM SALTS AND USES THEREOF CYPRESS PHARMACEUTICAL, INC. (US) 2009-10-29 US claimed
CN-100405924-C Magnesium supplementing feed additive having controlled slow-release type magnesium, its preparation and use method UNIV ZHEJIANG (CN) 2008-07-30 CN claimed
US-20070243232-A1 Method to treat and prevent asthma attacks using throat lozenges and orally-retained liquids containing magnesium EBY III GEORGE A 2007-10-18 US claimed
CN-1823610-A Magnesium supplementing feed additive having controlled slow-release type magnesium, its preparation and use method UNIV ZHEJIANG (CN) 2006-08-30 CN claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240408229-A1 CYCLODEXTRIN COMPLEXES OF SPECIALIZED PRORESOLVING MEDIATORS PTGER1, LTB4R2, ALOX5 GSR 1794/4885RNPEP 2760/4885GNAI3 1591/4885
US-12564644-B2 Cyclodextrin complexes of specialized proresolving mediators ALOX15, ALOX12, PTGES GSR 2736/4885RNPEP 3892/4885GNAI3 2830/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.