Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.61 |
| ▸ | CTSL | P07711 | 3/20 | 0.61 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.57 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.57 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.57 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.57 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.56 |
| ▸ | CDK4 | P11802 | 2/20 | 0.56 |
| ▸ | CCND1 | P24385 | 2/20 | 0.56 |
| ▸ | MAOA | P21397 | 3/20 | 0.55 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.52 |
| ▸ | PRKACA | P17612 | 1/20 | 0.52 |
| ▸ | PRKACG | P22612 | 1/20 | 0.52 |
| ▸ | PRKACB | P22694 | 1/20 | 0.52 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.52 |
| ▸ | CDK2 | P24941 | 1/20 | 0.52 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.49 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5879186 | 0.90 | MAOA (0.58) | CTSVCTSLGABRA1GABRG2GABRB3 | |
| SCHEMBL14422837 | 0.78 | CHEK1 (0.63) | CTSVCTSLGABRA1GABRG2GABRB3 | |
| SCHEMBL5879176 | 0.78 | CTSV (0.63) | CTSVCTSLCHEK1ALDH1A1HPGD | |
| SCHEMBL5879202 | 0.76 | CDK4 (0.62) | GABRA1GABRG2GABRB3GABRA3GABRA2 | |
| SCHEMBL177218 | 0.75 | CTSV (0.62) | CTSVCTSLMAOATNKS2PARP2 | |
| SCHEMBL14422827 | 0.75 | CTSV (0.83) | CTSVCTSLGABRA1GABRG2GABRB3 | |
| SCHEMBL2795363 | 0.75 | CTSV (0.65) | CTSVCTSLMAOATNKS2ALDH1A1 | |
| SCHEMBL17780933 | 0.74 | CTSV (0.64) | CTSVCTSLGABRA1GABRG2GABRB3 | |
| SCHEMBL5879271 | 0.74 | ADORA3 (0.53) | CTSVCTSLCHEK1ALDH1A1MAOB | |
| SCHEMBL6421417 | 0.74 | MAOB (0.81) | CTSVCTSLMAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7151108-B2 | Anticarcinogenic, antiproliferative, and antitumor agents | LES LABORATORIES SERVIER (FR) | 2006-12-19 | — | — | US | disclosed |
| EP-1411057-B1 | [3,4-a:3,4-c]carbazole derivatives, process for their preparation and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2005-04-27 | — | — | EP | disclosed |
| US-20040077672-A1 | Anticarcinogenic, antiproliferative, and antitumor agents | LES LABORATOIRES SERVIER (FR) | 2004-04-22 | — | — | US | disclosed |
| EP-1411057-A1 | [3,4-a:3,4-c]carbazole derivatives, process for their preparation and pharmaceutical compositions containing them | Les Laboratoires Servier (FR) | 2004-04-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040077672-A1 | Anticarcinogenic, antiproliferative, and antitumor agents | XDH, TOP2A, TOP1 | CTSV 4382/4885CTSL 4574/4885GABRA1 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.