Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.43 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.43 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.43 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1524281 | 0.82 | CETP (0.61) | LMNAPOLBL3MBTL1ALDH1A1PDK1 | |
| SCHEMBL10027976 | 0.81 | LMNA (0.59) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL19422611 | 0.80 | POLB (0.57) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL12963094 | 0.80 | LMNA (0.57) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL5879414 | 0.79 | LMNA (0.65) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL28741300 | 0.79 | LMNA (0.56) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL12863534 | 0.79 | POLB (0.56) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL6362837 | 0.78 | LMNA (0.55) | LMNAPOLBRIPK1L3MBTL1ALDH1A1 | |
| SCHEMBL12863541 | 0.78 | POLB (0.58) | LMNAPOLBRIPK1ALDH1A1GAA | |
| SCHEMBL28427502 | 0.78 | KDM4E (0.57) | LMNAPOLBRIPK1ALDH1A1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0903350-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 2003-03-12 | — | — | EP | disclosed |
| EP-0518238-B1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO LTD (JP) | 1999-04-07 | — | — | EP | disclosed |
| EP-0903350-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1999-03-24 | — | — | EP | disclosed |
| US-5508421-A | Pyrrolotriazole azomethine dye, and heat transfer dye providing material containing a pyrrolotriazole azomethine dye | FUJI PHOTO FILM CO., LTD. (JP) | 1996-04-16 | — | — | US | disclosed |
| US-5362882-A | Intermediates for dyes for polyesters, images for heat sensitive elements and electrography | FUJI PHOTO FILM CO., LTD. (JP) | 1994-11-08 | — | — | US | disclosed |
| EP-0518238-A1 | Pyrrolotriazole derivative | FUJI PHOTO FILM CO., LTD. (JP) | 1992-12-16 | — | — | EP | disclosed |