Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.45 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.45 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.45 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.45 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.45 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.45 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16500999 | 0.82 | CETP (0.61) | POLBLMNAALDH1A1GAATHRB | |
| SCHEMBL10027976 | 0.81 | LMNA (0.59) | POLBLMNARIPK1ALDH1A1GAA | |
| SCHEMBL7207413 | 0.80 | LMNA (0.61) | POLBLMNARIPK1ALDH1A1GAA | |
| SCHEMBL12963094 | 0.80 | LMNA (0.57) | POLBLMNARIPK1ALDH1A1GAA | |
| SCHEMBL7219667 | 0.79 | ALDH1A1 (0.54) | POLBLMNAALDH1A1GAATHRB | |
| SCHEMBL5879414 | 0.79 | LMNA (0.65) | POLBLMNARIPK1ALDH1A1GAA | |
| SCHEMBL28741300 | 0.79 | LMNA (0.56) | POLBLMNARIPK1ALDH1A1GAA | |
| SCHEMBL12863534 | 0.79 | POLB (0.56) | POLBLMNARIPK1ALDH1A1GAA | |
| SCHEMBL6448297 | 0.78 | ALDH1A1 (0.55) | POLBLMNAALDH1A1GAATHRB | |
| SCHEMBL6362837 | 0.78 | LMNA (0.55) | POLBLMNARIPK1ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10000458-B2 | Production method of 1, 2, 4-triazole compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-06-19 | — | — | US | disclosed |
| US-10000458-B2 | Production method of 1, 2, 4-triazole compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2018-06-19 | — | — | US | disclosed |
| US-20170283383-A1 | PRODUCTION METHOD OF 1, 2, 4-TRIAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-05 | — | — | US | disclosed |
| US-20170283383-A1 | PRODUCTION METHOD OF 1, 2, 4-TRIAZOLE COMPOUND | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2017-10-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10000458-B2 | Production method of 1, 2, 4-triazole compound | HRH4, HRH3, HRH2 | POLB 2953/4885LMNA 4356/4885RIPK1 3283/4885 |
| US-20170283383-A1 | PRODUCTION METHOD OF 1, 2, 4-TRIAZOLE COMPOUND | HRH4, HRH3, HRH2 | POLB 2953/4885LMNA 4356/4885RIPK1 3283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.